ID   MDH_THEAL               Reviewed;          23 AA.
AC   P33163;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Malate dehydrogenase;
DE            EC=1.1.1.37;
DE   Flags: Fragment;
GN   Name=mdh;
OS   Thermoleophilum album.
OC   Bacteria; Actinobacteria; Thermoleophilia; Thermoleophilales;
OC   Thermoleophilaceae; Thermoleophilum.
OX   NCBI_TaxID=29539;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=NM;
RA   Novotny J.F. Jr., Perry J.J.;
RT   "Characterization of the malate dehydrogenase from Thermoleophilum album
RT   NM.";
RL   Arch. Microbiol. 154:304-307(1990).
CC   -!- FUNCTION: Catalyzes the reversible oxidation of malate to oxaloacetate.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate;
CC         Xref=Rhea:RHEA:21432, ChEBI:CHEBI:15378, ChEBI:CHEBI:15589,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.37;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU10004};
CC   -!- SIMILARITY: Belongs to the LDH/MDH superfamily. MDH type 2 family.
CC       {ECO:0000305}.
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DR   PIR; A60689; A60689.
DR   AlphaFoldDB; P33163; -.
DR   GO; GO:0030060; F:L-malate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; NAD; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..>23
FT                   /note="Malate dehydrogenase"
FT                   /id="PRO_0000113397"
FT   NON_TER         23
SQ   SEQUENCE   23 AA;  2544 MW;  9B48F8218EF4F125 CRC64;
     MSILPLVHAM ANVRGDIEYL TEA