LOLB_PSEAE
ID LOLB_PSEAE Reviewed; 205 AA.
AC P42812;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 08-DEC-2000, sequence version 2.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Outer-membrane lipoprotein LolB;
DE Flags: Precursor;
GN Name=lolB; Synonyms=hemM; OrderedLocusNames=PA4668;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=7883699; DOI=10.1128/jb.177.6.1435-1443.1995;
RA Hungerer C., Troup B., Roemling U., Jahn D.;
RT "Regulation of the hemA gene during 5-aminolevulinic acid formation in
RT Pseudomonas aeruginosa.";
RL J. Bacteriol. 177:1435-1443(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Plays a critical role in the incorporation of lipoproteins in
CC the outer membrane after they are released by the LolA protein.
CC {ECO:0000250}.
CC -!- SUBUNIT: Monomer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Lipid-anchor
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LolB family. {ECO:0000305}.
CC -!- CAUTION: Was originally thought to be involved in delta-aminolevulinic
CC acid biosynthesis. {ECO:0000305}.
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DR EMBL; X82071; CAA57571.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG08055.1; -; Genomic_DNA.
DR PIR; E83063; E83063.
DR PIR; S49375; S49375.
DR RefSeq; NP_253357.1; NC_002516.2.
DR RefSeq; WP_003095005.1; NZ_QZGE01000029.1.
DR AlphaFoldDB; P42812; -.
DR SMR; P42812; -.
DR STRING; 287.DR97_1977; -.
DR PaxDb; P42812; -.
DR PRIDE; P42812; -.
DR DNASU; 881371; -.
DR EnsemblBacteria; AAG08055; AAG08055; PA4668.
DR GeneID; 881371; -.
DR KEGG; pae:PA4668; -.
DR PATRIC; fig|208964.12.peg.4890; -.
DR PseudoCAP; PA4668; -.
DR HOGENOM; CLU_092816_2_1_6; -.
DR InParanoid; P42812; -.
DR OMA; YQTRGSF; -.
DR PhylomeDB; P42812; -.
DR BioCyc; PAER208964:G1FZ6-4764-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044874; P:lipoprotein localization to outer membrane; IDA:CACAO.
DR GO; GO:0089705; P:protein localization to outer membrane; IDA:CACAO.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd16326; LolB; 1.
DR HAMAP; MF_00233; LolB; 1.
DR InterPro; IPR029046; LolA/LolB/LppX.
DR InterPro; IPR004565; OM_lipoprot_LolB.
DR Pfam; PF03550; LolB; 1.
DR SUPFAM; SSF89392; SSF89392; 1.
DR TIGRFAMs; TIGR00548; lolB; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Chaperone; Lipoprotein; Membrane; Palmitate;
KW Protein transport; Reference proteome; Signal; Transport.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..205
FT /note="Outer-membrane lipoprotein LolB"
FT /id="PRO_0000018306"
FT LIPID 18
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255"
FT LIPID 18
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255"
FT CONFLICT 116..121
FT /note="ALLEEQ -> STAGRT (in Ref. 1; CAA57571)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 205 AA; 23028 MW; 646BA206045A17C2 CRC64;
MRLRLFLAAS ALALLSGCAG LTSHEALEGQ GDAQTWKTHK QQLSELDAWQ IDGKVGIRAP
RDSGSGTLFW LQRQGYYDIR LSGPLGRGAA RLTGREGAVS LEVAGQGRYQ AESPEALLEE
QLGWRLPVSH LLWWVRGLPA PDSKSRLTLD ADSRLARLEQ DGWQIEYTRY AEQNGYWLPE
RLKLHGQDLD VTLVIKDWQP RQLGR
