ID   LOLB_HAEIN              Reviewed;         209 AA.
AC   P45270;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Outer-membrane lipoprotein LolB;
DE   Flags: Precursor;
GN   Name=lolB; Synonyms=hemM; OrderedLocusNames=HI_1607;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Plays a critical role in the incorporation of lipoproteins in
CC       the outer membrane after they are released by the LolA protein.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Lipid-anchor
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LolB family. {ECO:0000305}.
CC   -!- CAUTION: Was originally thought to be involved in delta-aminolevulinic
CC       acid biosynthesis. {ECO:0000305}.
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DR   EMBL; L42023; AAC23251.1; -; Genomic_DNA.
DR   PIR; I64172; I64172.
DR   RefSeq; NP_439749.1; NC_000907.1.
DR   AlphaFoldDB; P45270; -.
DR   SMR; P45270; -.
DR   STRING; 71421.HI_1607; -.
DR   EnsemblBacteria; AAC23251; AAC23251; HI_1607.
DR   KEGG; hin:HI_1607; -.
DR   PATRIC; fig|71421.8.peg.1680; -.
DR   eggNOG; COG3017; Bacteria.
DR   HOGENOM; CLU_092816_1_1_6; -.
DR   OMA; YQTRGSF; -.
DR   PhylomeDB; P45270; -.
DR   BioCyc; HINF71421:G1GJ1-1620-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044874; P:lipoprotein localization to outer membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd16326; LolB; 1.
DR   HAMAP; MF_00233; LolB; 1.
DR   InterPro; IPR029046; LolA/LolB/LppX.
DR   InterPro; IPR004565; OM_lipoprot_LolB.
DR   Pfam; PF03550; LolB; 1.
DR   SUPFAM; SSF89392; SSF89392; 1.
DR   TIGRFAMs; TIGR00548; lolB; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Chaperone; Lipoprotein; Membrane; Palmitate;
KW   Protein transport; Reference proteome; Signal; Transport.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..209
FT                   /note="Outer-membrane lipoprotein LolB"
FT                   /id="PRO_0000018300"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   209 AA;  24193 MW;  0555F02F13E852A1 CRC64;
     MNNMKTFKFF TALFATAILT ACTLDMERPT NVQYIDKTDA IWQQHLQKIQ KIQSYQAKGQ
     IGYISPTERF SSRFEWQYQN PKSYTLKLYS LISKSTLWIQ MHQSGMTISD NNGNQQSAAN
     SKLLLQEIIG MDVPLEHLAY WLKGQPAMNA DYQVGTNHLL GAFTYHVDGS QWTADYLTYH
     SNNSMPENIL LKNDSTKQTL KIRVDEWIY