ID   LOLA_HELP2              Reviewed;         184 AA.
AC   B6JM17;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Outer-membrane lipoprotein carrier protein {ECO:0000255|HAMAP-Rule:MF_00240};
DE   Flags: Precursor;
GN   Name=lolA {ECO:0000255|HAMAP-Rule:MF_00240}; OrderedLocusNames=HPP12_0793;
OS   Helicobacter pylori (strain P12).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=570508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P12;
RA   Fischer W., Windhager L., Karnholz A., Zeiller M., Zimmer R., Haas R.;
RT   "The complete genome sequence of Helicobacter pylori strain P12.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in the translocation of lipoproteins from the
CC       inner membrane to the outer membrane. Only forms a complex with a
CC       lipoprotein if the residue after the N-terminal Cys is not an aspartate
CC       (The Asp acts as a targeting signal to indicate that the lipoprotein
CC       should stay in the inner membrane). {ECO:0000255|HAMAP-Rule:MF_00240}.
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00240}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00240}.
CC   -!- SIMILARITY: Belongs to the LolA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00240}.
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DR   EMBL; CP001217; ACJ07945.1; -; Genomic_DNA.
DR   RefSeq; WP_000643103.1; NC_011498.1.
DR   AlphaFoldDB; B6JM17; -.
DR   SMR; B6JM17; -.
DR   EnsemblBacteria; ACJ07945; ACJ07945; HPP12_0793.
DR   KEGG; hpp:HPP12_0793; -.
DR   HOGENOM; CLU_125914_0_0_7; -.
DR   OMA; IYMNDKE; -.
DR   OrthoDB; 1933827at2; -.
DR   Proteomes; UP000008198; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0044874; P:lipoprotein localization to outer membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR   CDD; cd16325; LolA; 1.
DR   HAMAP; MF_00240; LolA; 1.
DR   InterPro; IPR029046; LolA/LolB/LppX.
DR   InterPro; IPR004564; OM_lipoprot_carrier_LolA-like.
DR   InterPro; IPR018323; OM_lipoprot_carrier_LolA_Pbac.
DR   PANTHER; PTHR35869; PTHR35869; 1.
DR   Pfam; PF03548; LolA; 1.
DR   SUPFAM; SSF89392; SSF89392; 1.
PE   3: Inferred from homology;
KW   Chaperone; Periplasm; Protein transport; Signal; Transport.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00240"
FT   CHAIN           20..184
FT                   /note="Outer-membrane lipoprotein carrier protein"
FT                   /id="PRO_1000100720"
SQ   SEQUENCE   184 AA;  21405 MW;  543381BFE9BC0D00 CRC64;
     MKAFLKILMV LIFVSVAYAK SPPTLSKEEE VLQHLQSFSA HFKQVLKNEK PLVYYGVLKA
     KAPNWALWVY EKPLKKEIYM NDKEVVIYEP NLFQATITPL KDKTDFFTIL KRLKKQDDGS
     FKTTINKTTY RLVFKDGKPF SLEFKDGMNN LVTITFSQAE INPTIADEIF VFKPKDENID
     IVRQ