ID   KUP_CAUVN               Reviewed;         665 AA.
AC   B8GXM1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=CCNA_00130;
OS   Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=565050;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA1000 / CB15N;
RX   PubMed=20472802; DOI=10.1128/jb.00255-10;
RA   Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V.,
RA   Walunas T.L., Crosson S.;
RT   "The genetic basis of laboratory adaptation in Caulobacter crescentus.";
RL   J. Bacteriol. 192:3678-3688(2010).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP001340; ACL93597.1; -; Genomic_DNA.
DR   RefSeq; WP_012639885.1; NC_011916.1.
DR   RefSeq; YP_002515505.1; NC_011916.1.
DR   AlphaFoldDB; B8GXM1; -.
DR   PRIDE; B8GXM1; -.
DR   EnsemblBacteria; ACL93597; ACL93597; CCNA_00130.
DR   GeneID; 7332384; -.
DR   KEGG; ccs:CCNA_00130; -.
DR   PATRIC; fig|565050.3.peg.129; -.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   PhylomeDB; B8GXM1; -.
DR   Proteomes; UP000001364; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..665
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_1000185114"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        332..352
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        409..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        435..455
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        462..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   665 AA;  71548 MW;  F86362DF60AECB18 CRC64;
     MASEAPHASA PDCAPASSDI PQQDGGSTNG HGHDLKGHGF FALALGSVGV VFGDIGTSPL
     YAFKEALAAA SHDGVTRSEI FGVVSLALWA LILIVTIKYV VFIMRADNKG EGGVLSLMAL
     AQHAMGKRTT LVFVLGVAGA ALFYGDAVIT PAMSVLSAVE GLRTIPALEH GVTNEVVLLI
     ATVMLLGLFF IQSRGTASVG KLFGPVCAVW FGVMFSLGLM NLAANPGILM AISPYYAVEF
     LAEHGLTGFI VLGAVFLTVT GVEALTADMG HFGRWPIQAA WLFFVLPCLA MNYLGQGAFA
     LTTLETAQAA GKAMPELNWF FEMAPEALRL PLVLLAGAAT VIASQAVITG AFSLTQQAIQ
     LGLLPRLDVR RTSETQSGQI FVPQLNTMLL LGVLAIMFTF QTSSALAHAY GLAVTGTMIV
     TTCMAFIVMR KLWKWSMPMA LLFLVPFLAL DITFLSANAL RFFSGGWLPV LIGAALFTIM
     ATWVRGSQIL TDKTRRDSLP VADLMDILRA RAPHRAPGTA IFLTSDPDMT PVALMHNLKH
     NKVLHERNVI LTVRTAETPR VSEEERVKIE KVNDDFKKVV VNYGFMESPN IPKALAVCRK
     QGLKFDIMAT SFFLGRRSIV PSANSGMPLW QDRLFIYLMR NAANPTDFFK IPPGRVVELG
     AQVTV