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KORC_METTH
ID   KORC_METTH              Reviewed;         189 AA.
AC   O27114;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=2-oxoglutarate synthase subunit KorC;
DE            EC=1.2.7.3;
DE   AltName: Full=2-ketoglutarate oxidoreductase gamma chain;
DE            Short=KOR;
DE   AltName: Full=2-oxoglutarate-ferredoxin oxidoreductase subunit gamma;
GN   Name=korC; OrderedLocusNames=MTH_1035;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2
CC         + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA;
CC         Xref=Rhea:RHEA:17297, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:16810,
CC         ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57292; EC=1.2.7.3;
CC   -!- SUBUNIT: Heterotetramer of the KorA, KorB, KorC and KorD subunits.
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DR   EMBL; AE000666; AAB85531.1; -; Genomic_DNA.
DR   PIR; B69005; B69005.
DR   AlphaFoldDB; O27114; -.
DR   SMR; O27114; -.
DR   STRING; 187420.MTH_1035; -.
DR   EnsemblBacteria; AAB85531; AAB85531; MTH_1035.
DR   KEGG; mth:MTH_1035; -.
DR   PATRIC; fig|187420.15.peg.1018; -.
DR   HOGENOM; CLU_087284_0_0_2; -.
DR   OMA; EVSWMPS; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.920.10; -; 1.
DR   InterPro; IPR011894; PorC_KorC.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   Pfam; PF01558; POR; 1.
DR   SUPFAM; SSF53323; SSF53323; 1.
DR   TIGRFAMs; TIGR02175; PorC_KorC; 1.
PE   4: Predicted;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..189
FT                   /note="2-oxoglutarate synthase subunit KorC"
FT                   /id="PRO_0000099947"
SQ   SEQUENCE   189 AA;  20380 MW;  335EF064D7318C3C CRC64;
     MIEVRKEIRI AGFGGQGVIL AGIVLGKAAS LYDGLYAVQT QSYGPEARGG ASRAEVVISD
     HEIDYPKVQS PDILVAMSHQ ALLTYMDDLK RGGALIVDPD MVVEAEIEDF IRAREVKYFR
     APATRTAEER VGITIVANMV MIGALTEATG IVSVRAAEEA IKDSVPPGTE EKNLMAFQAG
     RELIMEGSR
 
 
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