KAIB_TRIV2
ID KAIB_TRIV2 Reviewed; 108 AA.
AC Q3MEE5;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2005, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Circadian clock protein KaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN Name=kaiB {ECO:0000255|HAMAP-Rule:MF_01835}; OrderedLocusNames=Ava_1017;
OS Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis).
OC Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Trichormus.
OX NCBI_TaxID=240292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29413 / PCC 7937;
RX PubMed=25197444; DOI=10.4056/sigs.3899418;
RA Thiel T., Pratte B.S., Zhong J., Goodwin L., Copeland A., Lucas S., Han C.,
RA Pitluck S., Land M.L., Kyrpides N.C., Woyke T.;
RT "Complete genome sequence of Anabaena variabilis ATCC 29413.";
RL Stand. Genomic Sci. 9:562-573(2014).
CC -!- FUNCTION: Component of the KaiABC clock protein complex, which
CC constitutes the main circadian regulator in cyanobacteria. The KaiABC
CC complex may act as a promoter-non-specific transcription regulator that
CC represses transcription, possibly by acting on the state of chromosome
CC compaction. In the complex, it decreases the phosphorylation status of
CC KaiC. It has no effect on KaiC by itself, but instead needs the
CC presence of both KaiA and KaiC, suggesting that it acts by antagonizing
CC the interaction between KaiA and KaiC. {ECO:0000255|HAMAP-
CC Rule:MF_01835}.
CC -!- SUBUNIT: Homodimer. Component of the KaiABC complex, at least composed
CC of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. The KaiABC
CC complex also interacts with SasA. {ECO:0000255|HAMAP-Rule:MF_01835}.
CC -!- SIMILARITY: Belongs to the KaiB family. {ECO:0000255|HAMAP-
CC Rule:MF_01835}.
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DR EMBL; CP000117; ABA20641.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3MEE5; -.
DR SMR; Q3MEE5; -.
DR STRING; 240292.Ava_1017; -.
DR EnsemblBacteria; ABA20641; ABA20641; Ava_1017.
DR KEGG; ava:Ava_1017; -.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_144073_0_0_3; -.
DR OMA; NEFKGVY; -.
DR Proteomes; UP000002533; Chromosome.
DR GO; GO:0007623; P:circadian rhythm; IEA:UniProtKB-UniRule.
DR GO; GO:0042326; P:negative regulation of phosphorylation; IEA:InterPro.
DR CDD; cd02978; KaiB_like; 1.
DR HAMAP; MF_01835; KaiB; 1.
DR InterPro; IPR013474; Circ_KaiB.
DR InterPro; IPR039022; KaiB-like.
DR InterPro; IPR011649; KaiB_domain.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR41709; PTHR41709; 1.
DR Pfam; PF07689; KaiB; 1.
DR SMART; SM01248; KaiB; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR TIGRFAMs; TIGR02654; circ_KaiB; 1.
PE 3: Inferred from homology;
KW Biological rhythms.
FT CHAIN 1..108
FT /note="Circadian clock protein KaiB"
FT /id="PRO_1000070456"
SQ SEQUENCE 108 AA; 12249 MW; 6DDE0C8184BA28B2 CRC64;
MNKARKTYVL KLYVAGNTPN SVRALKTLKN ILEQEFQGIY ALKVIDVLKN PQLAEEDKIL
ATPTLSKILP PPVRKIIGDL SDRERVLIGL DLLYEELTEE DWEAQSSL