ID   KAIB_THEVL              Reviewed;         108 AA.
AC   Q6L8K0;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Circadian clock protein KaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN   Name=kaiB {ECO:0000255|HAMAP-Rule:MF_01835};
OS   Thermostichus vulcanus (Synechococcus vulcanus).
OC   Bacteria; Cyanobacteria; Thermostichales; Thermostichaceae; Thermostichus.
OX   NCBI_TaxID=32053;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15170179; DOI=10.1038/nsmb781;
RA   Uzumaki T., Fujita M., Nakatsu T., Hayashi F., Shibata H., Itoh N.,
RA   Kato H., Ishiura M.;
RT   "Crystal structure of the C-terminal clock-oscillator domain of the
RT   cyanobacterial KaiA protein.";
RL   Nat. Struct. Mol. Biol. 11:623-631(2004).
CC   -!- FUNCTION: Component of the KaiABC clock protein complex, which
CC       constitutes the main circadian regulator in cyanobacteria. The KaiABC
CC       complex may act as a promoter-non-specific transcription regulator that
CC       represses transcription, possibly by acting on the state of chromosome
CC       compaction. In the complex, it decreases the phosphorylation status of
CC       KaiC. It has no effect on KaiC by itself, but instead needs the
CC       presence of both KaiA and KaiC, suggesting that it acts by antagonizing
CC       the interaction between KaiA and KaiC. {ECO:0000255|HAMAP-
CC       Rule:MF_01835}.
CC   -!- SUBUNIT: Homodimer. Component of the KaiABC complex, at least composed
CC       of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. The KaiABC
CC       complex also interacts with SasA. {ECO:0000255|HAMAP-Rule:MF_01835}.
CC   -!- SIMILARITY: Belongs to the KaiB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01835}.
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DR   EMBL; AB121971; BAD21222.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6L8K0; -.
DR   SMR; Q6L8K0; -.
DR   GO; GO:0007623; P:circadian rhythm; IEA:UniProtKB-UniRule.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IEA:InterPro.
DR   CDD; cd02978; KaiB_like; 1.
DR   HAMAP; MF_01835; KaiB; 1.
DR   InterPro; IPR013474; Circ_KaiB.
DR   InterPro; IPR039022; KaiB-like.
DR   InterPro; IPR011649; KaiB_domain.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR41709; PTHR41709; 1.
DR   Pfam; PF07689; KaiB; 1.
DR   SMART; SM01248; KaiB; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02654; circ_KaiB; 1.
PE   3: Inferred from homology;
KW   Biological rhythms.
FT   CHAIN           1..108
FT                   /note="Circadian clock protein KaiB"
FT                   /id="PRO_0000217770"
SQ   SEQUENCE   108 AA;  12025 MW;  BC6B71EFBE6254E3 CRC64;
     MAPLRKTYVL KLYVAGNTPN SVRALKTLNN ILEKEFKGVY ALKVIDVLKN PQLAEEDKIL
     ATPTLAKVLP PPVRRIIGDL SNREKVLIGL DLLYEEIGDQ AEDDLGLE