ID   KAIB_THEVB              Reviewed;         108 AA.
AC   Q79V61; Q8RR34;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Circadian clock protein KaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN   Name=kaiB {ECO:0000255|HAMAP-Rule:MF_01835}; OrderedLocusNames=tlr0482;
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=12622725; DOI=10.1046/j.1365-2443.2003.00633.x;
RA   Hayashi F., Suzuki H., Iwase R., Uzumaki T., Miyake A., Shen J.-R.,
RA   Imada K., Furukawa Y., Yonekura K., Namba K., Ishiura M.;
RT   "ATP-induced hexameric ring structure of the cyanobacterial circadian clock
RT   protein KaiC.";
RL   Genes Cells 8:287-296(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
CC   -!- FUNCTION: Component of the KaiABC clock protein complex, which
CC       constitutes the main circadian regulator in cyanobacteria. The KaiABC
CC       complex may act as a promoter-non-specific transcription regulator that
CC       represses transcription, possibly by acting on the state of chromosome
CC       compaction. In the complex, it decreases the phosphorylation status of
CC       KaiC. It has no effect on KaiC by itself, but instead needs the
CC       presence of both KaiA and KaiC, suggesting that it acts by antagonizing
CC       the interaction between KaiA and KaiC. {ECO:0000255|HAMAP-
CC       Rule:MF_01835}.
CC   -!- SUBUNIT: Homodimer. Component of the KaiABC complex, at least composed
CC       of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. The KaiABC
CC       complex also interacts with SasA. {ECO:0000255|HAMAP-Rule:MF_01835}.
CC   -!- INTERACTION:
CC       Q79V61; Q79V60: kaiC; NbExp=6; IntAct=EBI-7570699, EBI-701595;
CC   -!- SIMILARITY: Belongs to the KaiB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01835}.
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DR   EMBL; AB071375; BAB85984.1; -; Genomic_DNA.
DR   EMBL; BA000039; BAC08034.1; -; Genomic_DNA.
DR   RefSeq; NP_681272.1; NC_004113.1.
DR   RefSeq; WP_011056333.1; NC_004113.1.
DR   PDB; 1VGL; X-ray; 2.60 A; A/B/C/D=1-108.
DR   PDB; 2QKE; X-ray; 2.70 A; A/B/C/D/E/F=1-108.
DR   PDB; 5JWO; X-ray; 1.80 A; B=1-99.
DR   PDB; 5JWQ; X-ray; 3.87 A; B/D=1-99.
DR   PDB; 5JWR; X-ray; 2.61 A; B/D=1-99.
DR   PDB; 5JYT; NMR; -; A=1-99.
DR   PDB; 5JYV; NMR; -; B=1-99.
DR   PDBsum; 1VGL; -.
DR   PDBsum; 2QKE; -.
DR   PDBsum; 5JWO; -.
DR   PDBsum; 5JWQ; -.
DR   PDBsum; 5JWR; -.
DR   PDBsum; 5JYT; -.
DR   PDBsum; 5JYV; -.
DR   AlphaFoldDB; Q79V61; -.
DR   SMR; Q79V61; -.
DR   DIP; DIP-29356N; -.
DR   IntAct; Q79V61; 1.
DR   MINT; Q79V61; -.
DR   STRING; 197221.22294203; -.
DR   EnsemblBacteria; BAC08034; BAC08034; BAC08034.
DR   KEGG; tel:tlr0482; -.
DR   PATRIC; fig|197221.4.peg.507; -.
DR   eggNOG; COG4251; Bacteria.
DR   OMA; NEFKGVY; -.
DR   OrthoDB; 1999883at2; -.
DR   EvolutionaryTrace; Q79V61; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0007623; P:circadian rhythm; IEA:UniProtKB-UniRule.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IEA:InterPro.
DR   CDD; cd02978; KaiB_like; 1.
DR   HAMAP; MF_01835; KaiB; 1.
DR   InterPro; IPR013474; Circ_KaiB.
DR   InterPro; IPR039022; KaiB-like.
DR   InterPro; IPR011649; KaiB_domain.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR41709; PTHR41709; 1.
DR   Pfam; PF07689; KaiB; 1.
DR   SMART; SM01248; KaiB; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02654; circ_KaiB; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Biological rhythms; Reference proteome.
FT   CHAIN           1..108
FT                   /note="Circadian clock protein KaiB"
FT                   /id="PRO_0000217765"
FT   STRAND          8..14
FT                   /evidence="ECO:0007829|PDB:5JWO"
FT   HELIX           19..33
FT                   /evidence="ECO:0007829|PDB:5JWO"
FT   TURN            34..39
FT                   /evidence="ECO:0007829|PDB:5JWO"
FT   STRAND          40..46
FT                   /evidence="ECO:0007829|PDB:5JWO"
FT   TURN            47..49
FT                   /evidence="ECO:0007829|PDB:5JWO"
FT   HELIX           51..57
FT                   /evidence="ECO:0007829|PDB:5JWO"
FT   STRAND          58..60
FT                   /evidence="ECO:0007829|PDB:1VGL"
FT   STRAND          61..72
FT                   /evidence="ECO:0007829|PDB:5JWO"
FT   STRAND          74..78
FT                   /evidence="ECO:0007829|PDB:5JWO"
FT   HELIX           83..93
FT                   /evidence="ECO:0007829|PDB:5JWO"
SQ   SEQUENCE   108 AA;  12025 MW;  BC6B71EFBE6254E3 CRC64;
     MAPLRKTYVL KLYVAGNTPN SVRALKTLNN ILEKEFKGVY ALKVIDVLKN PQLAEEDKIL
     ATPTLAKVLP PPVRRIIGDL SNREKVLIGL DLLYEEIGDQ AEDDLGLE