ID   KAIB_SYNP2              Reviewed;         104 AA.
AC   Q6L8L6; B1XMW1;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Circadian clock protein KaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN   Name=kaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN   OrderedLocusNames=SYNPCC7002_A0288;
OS   Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum
OS   quadruplicatum).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=32049;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15170179; DOI=10.1038/nsmb781;
RA   Uzumaki T., Fujita M., Nakatsu T., Hayashi F., Shibata H., Itoh N.,
RA   Kato H., Ishiura M.;
RT   "Crystal structure of the C-terminal clock-oscillator domain of the
RT   cyanobacterial KaiA protein.";
RL   Nat. Struct. Mol. Biol. 11:623-631(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27264 / PCC 7002 / PR-6;
RA   Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T.,
RA   Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J.,
RA   Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.;
RT   "Complete sequence of Synechococcus sp. PCC 7002.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the KaiABC clock protein complex, which
CC       constitutes the main circadian regulator in cyanobacteria. The KaiABC
CC       complex may act as a promoter-non-specific transcription regulator that
CC       represses transcription, possibly by acting on the state of chromosome
CC       compaction. In the complex, it decreases the phosphorylation status of
CC       KaiC. It has no effect on KaiC by itself, but instead needs the
CC       presence of both KaiA and KaiC, suggesting that it acts by antagonizing
CC       the interaction between KaiA and KaiC. {ECO:0000255|HAMAP-
CC       Rule:MF_01835}.
CC   -!- SUBUNIT: Homodimer. Component of the KaiABC complex, at least composed
CC       of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. The KaiABC
CC       complex also interacts with SasA. {ECO:0000255|HAMAP-Rule:MF_01835}.
CC   -!- SIMILARITY: Belongs to the KaiB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01835}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACA98298.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AB120711; BAD21212.1; -; Genomic_DNA.
DR   EMBL; CP000951; ACA98298.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_030006078.1; NC_010475.1.
DR   AlphaFoldDB; Q6L8L6; -.
DR   SMR; Q6L8L6; -.
DR   STRING; 32049.SYNPCC7002_A0288; -.
DR   EnsemblBacteria; ACA98298; ACA98298; SYNPCC7002_A0288.
DR   KEGG; syp:SYNPCC7002_A0288; -.
DR   eggNOG; COG4251; Bacteria.
DR   HOGENOM; CLU_144073_0_0_3; -.
DR   OMA; NEFKGVY; -.
DR   Proteomes; UP000001688; Chromosome.
DR   GO; GO:0007623; P:circadian rhythm; IEA:UniProtKB-UniRule.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IEA:InterPro.
DR   CDD; cd02978; KaiB_like; 1.
DR   HAMAP; MF_01835; KaiB; 1.
DR   InterPro; IPR013474; Circ_KaiB.
DR   InterPro; IPR039022; KaiB-like.
DR   InterPro; IPR011649; KaiB_domain.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR41709; PTHR41709; 1.
DR   Pfam; PF07689; KaiB; 1.
DR   SMART; SM01248; KaiB; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02654; circ_KaiB; 1.
PE   3: Inferred from homology;
KW   Biological rhythms; Reference proteome.
FT   CHAIN           1..104
FT                   /note="Circadian clock protein KaiB"
FT                   /id="PRO_0000217766"
FT   CONFLICT        48
FT                   /note="L -> F (in Ref. 1; BAD21212)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        52
FT                   /note="Q -> K (in Ref. 1; BAD21212)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        65
FT                   /note="L -> F (in Ref. 1; BAD21212)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   104 AA;  11808 MW;  E8F5A840D45C27BD CRC64;
     MNLLKKTYVL KLYVAGNTPN SVRALKTLKN ILETDFKGVY ALKVIDVLQN PQLAEEDKIL
     ATPTLSKVLP PPVRKIIGDL SDREKVLIGL DLLYEEFLER EEEL