KAIB_CYAP4
ID KAIB_CYAP4 Reviewed; 105 AA.
AC B8HSU2;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Circadian clock protein KaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN Name=kaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN OrderedLocusNames=Cyan7425_0347;
OS Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC Cyanothecaceae; Cyanothece; unclassified Cyanothece.
OX NCBI_TaxID=395961;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7425 / ATCC 29141;
RX PubMed=21972240; DOI=10.1128/mbio.00214-11;
RA Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA Sherman L.A., Pakrasi H.B.;
RT "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT unicellular nitrogen-fixing Cyanobacteria.";
RL MBio 2:E214-E214(2011).
CC -!- FUNCTION: Component of the KaiABC clock protein complex, which
CC constitutes the main circadian regulator in cyanobacteria. The KaiABC
CC complex may act as a promoter-non-specific transcription regulator that
CC represses transcription, possibly by acting on the state of chromosome
CC compaction. In the complex, it decreases the phosphorylation status of
CC KaiC. It has no effect on KaiC by itself, but instead needs the
CC presence of both KaiA and KaiC, suggesting that it acts by antagonizing
CC the interaction between KaiA and KaiC. {ECO:0000255|HAMAP-
CC Rule:MF_01835}.
CC -!- SUBUNIT: Homodimer. Component of the KaiABC complex, at least composed
CC of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. The KaiABC
CC complex also interacts with SasA. {ECO:0000255|HAMAP-Rule:MF_01835}.
CC -!- SIMILARITY: Belongs to the KaiB family. {ECO:0000255|HAMAP-
CC Rule:MF_01835}.
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DR EMBL; CP001344; ACL42739.1; -; Genomic_DNA.
DR RefSeq; WP_012625841.1; NC_011884.1.
DR AlphaFoldDB; B8HSU2; -.
DR SMR; B8HSU2; -.
DR STRING; 395961.Cyan7425_0347; -.
DR EnsemblBacteria; ACL42739; ACL42739; Cyan7425_0347.
DR KEGG; cyn:Cyan7425_0347; -.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_144073_0_0_3; -.
DR OMA; NEFKGVY; -.
DR OrthoDB; 1999883at2; -.
DR GO; GO:0007623; P:circadian rhythm; IEA:UniProtKB-UniRule.
DR GO; GO:0042326; P:negative regulation of phosphorylation; IEA:InterPro.
DR CDD; cd02978; KaiB_like; 1.
DR HAMAP; MF_01835; KaiB; 1.
DR InterPro; IPR013474; Circ_KaiB.
DR InterPro; IPR039022; KaiB-like.
DR InterPro; IPR011649; KaiB_domain.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR41709; PTHR41709; 1.
DR Pfam; PF07689; KaiB; 1.
DR SMART; SM01248; KaiB; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR TIGRFAMs; TIGR02654; circ_KaiB; 1.
PE 3: Inferred from homology;
KW Biological rhythms.
FT CHAIN 1..105
FT /note="Circadian clock protein KaiB"
FT /id="PRO_1000188345"
SQ SEQUENCE 105 AA; 11692 MW; EB7E683AB9432CEC CRC64;
MSPLKKTYVL KLYVAGNTPN SVRALKTLNN ILEQEFQGVY ALKVIDVLKN PQLAEEDKIL
ATPTLAKILP PPVRKIIGDL SDREKVLIGL DLLYEEFAEA EAEAE