ID   INSH5_ECOLI             Reviewed;         326 AA.
AC   P76071; P77749;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Transposase InsH for insertion sequence element IS5Y;
GN   Name=insH5; OrderedLocusNames=b1370, JW1363;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence IS5.
CC   -!- SIMILARITY: Belongs to the transposase 11 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00096; AAC74452.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA14963.2; -; Genomic_DNA.
DR   PIR; E64887; E64887.
DR   PIR; T09186; T09186.
DR   RefSeq; NP_415888.1; NC_000913.3.
DR   RefSeq; WP_000019448.1; NZ_CP011343.2.
DR   AlphaFoldDB; P76071; -.
DR   STRING; 511145.b1370; -.
DR   jPOST; P76071; -.
DR   PaxDb; P76071; -.
DR   PRIDE; P76071; -.
DR   EnsemblBacteria; BAA14963; BAA14963; BAA14963.
DR   GeneID; 945944; -.
DR   KEGG; ecj:JW1363; -.
DR   KEGG; eco:b1370; -.
DR   PATRIC; fig|83333.103.peg.2184; -.
DR   EchoBASE; EB4723; -.
DR   eggNOG; COG3039; Bacteria.
DR   HOGENOM; CLU_049873_1_1_6; -.
DR   InParanoid; P76071; -.
DR   OMA; VEHIFGF; -.
DR   PhylomeDB; P76071; -.
DR   BioCyc; EcoCyc:G6693-MON; -.
DR   PRO; PR:P76071; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:EcoCyc.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   InterPro; IPR002559; Transposase_11.
DR   InterPro; IPR008490; Transposase_InsH_N.
DR   Pfam; PF01609; DDE_Tnp_1; 1.
DR   Pfam; PF05598; DUF772; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW   Transposition.
FT   CHAIN           1..326
FT                   /note="Transposase InsH for insertion sequence element
FT                   IS5Y"
FT                   /id="PRO_0000173293"
SQ   SEQUENCE   326 AA;  37777 MW;  1A3C80D7FD5D8B5B CRC64;
     MSHQLTFADS EFSTKRRQTR KEIFLSRMEQ ILPWQNMTAV IEPFYPKAGN GRRPYPLETM
     LRIHCMQHWY NLSDGAMEDA LYEIASMRLF ARLSLDSALP DRTTIMNFRH LLEQHQLARQ
     LFKTINRWLA EAGVMMTQGT LVDATIIEAP SSTKNKEQQR DPEMHQTKKG NQWHFGMKAH
     IGVDAKSGLT HSLVTTAANE HDLNQLGNLL HGEEQFVSAD AGYQGAPQRE ELAEVDVDWL
     IAERPGKVKT LKQNPRKNKT AINIEYMKAS IRARVEHPFR IIKRQFGFVK ARYKGLLKND
     NQLAMLFTLA NLFRVDQMIR QWERSQ