INSH1_ECOLI
ID INSH1_ECOLI Reviewed; 326 AA.
AC P0CE49; O07987; O07988; P03837; P76355; Q2MBK1; Q2MBM8;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 17-JUN-2020, sequence version 2.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=Transposase InsH for insertion sequence element IS5A;
GN Name=insH1; OrderedLocusNames=b0259, JW0250;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6269959; DOI=10.1016/0378-1119(81)90112-8;
RA Schoner B., Kahn M.;
RT "The nucleotide sequence of IS5 from Escherichia coli.";
RL Gene 14:165-174(1981).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6269958; DOI=10.1016/0378-1119(81)90111-6;
RA Engler J.A., van Bree M.P.;
RT "The nucleotide sequence and protein-coding capability of the transposable
RT element IS5.";
RL Gene 14:155-163(1981).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT from 76.0 to 81.5 minutes.";
RL Nucleic Acids Res. 22:2576-2586(1994).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA Horiuchi T.;
RT "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 40.1-50.0 min region on the linkage map.";
RL DNA Res. 3:379-392(1996).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence IS5.
CC -!- SIMILARITY: Belongs to the transposase 11 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB08679.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAC73362.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAE76049.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; J01734; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; U70214; AAB08679.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; AAC73362.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP009048; BAE76049.1; ALT_INIT; Genomic_DNA.
DR PIR; A64964; A64964.
DR PIR; A91483; IEEC5D.
DR RefSeq; NP_414793.1; NC_000913.3.
DR RefSeq; NP_415084.1; NC_000913.3.
DR RefSeq; NP_415189.1; NC_000913.3.
DR RefSeq; NP_415847.1; NC_000913.3.
DR RefSeq; NP_416535.1; NC_000913.3.
DR RefSeq; NP_416696.1; NC_000913.3.
DR RefSeq; NP_417456.1; NC_000913.3.
DR RefSeq; NP_417685.1; NC_000913.3.
DR RefSeq; NP_417962.1; NC_000913.3.
DR AlphaFoldDB; P0CE49; -.
DR jPOST; P0CE49; -.
DR PRIDE; P0CE49; -.
DR EnsemblBacteria; AAC73362; AAC73362; b0259.
DR EnsemblBacteria; BAE76049; BAE76049; BAE76049.
DR GeneID; 944917; -.
DR GeneID; 944941; -.
DR GeneID; 945896; -.
DR GeneID; 946163; -.
DR GeneID; 946577; -.
DR GeneID; 947516; -.
DR GeneID; 947743; -.
DR GeneID; 948015; -.
DR GeneID; 949121; -.
DR KEGG; ecj:JW0250; -.
DR KEGG; eco:b0259; -.
DR KEGG; eco:b0552; -.
DR KEGG; eco:b0656; -.
DR KEGG; eco:b1331; -.
DR KEGG; eco:b2030; -.
DR KEGG; eco:b2192; -.
DR KEGG; eco:b2982; -.
DR KEGG; eco:b3218; -.
DR KEGG; eco:b3505; -.
DR EchoBASE; EB4704; -.
DR HOGENOM; CLU_049873_1_2_6; -.
DR InParanoid; P0CE49; -.
DR PhylomeDB; P0CE49; -.
DR BioCyc; EcoCyc:G7769-MON; -.
DR PRO; PR:P0CE49; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR InterPro; IPR002559; Transposase_11.
DR InterPro; IPR008490; Transposase_InsH_N.
DR Pfam; PF01609; DDE_Tnp_1; 1.
DR Pfam; PF05598; DUF772; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW Transposition.
FT CHAIN 1..326
FT /note="Transposase InsH for insertion sequence element
FT IS5A"
FT /id="PRO_0000173292"
SQ SEQUENCE 326 AA; 37851 MW; 07FD70483E9E922E CRC64;
MSHQLTFADS EFSSKRRQTR KEIFLSRMEQ ILPWQNMVEV IEPFYPKAGN GRRPYPLETM
LRIHCMQHWY NLSDGAMEDA LYEIASMRLF ARLSLDSALP DRTTIMNFRH LLEQHQLARQ
LFKTINRWLA EAGVMMTQGT LVDATIIEAP SSTKNKEQQR DPEMHQTKKG NQWHFGMKAH
IGVDAKSGLT HSLVTTAANE HDLNQLGNLL HGEEQFVSAD AGYQGAPQRE ELAEVDVDWL
IAERPGKVRT LKQHPRKNKT AINIEYMKAS IRARVEHPFR IIKRQFGFVK ARYKGLLKND
NQLAMLFTLA NLFRADQMIR QWERSH
