ID   INSF6_ECOLI             Reviewed;         288 AA.
AC   P0CF84; O08009; O08012; O08304; P05822; P77673; Q2MBI8;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Transposase InsF for insertion sequence IS3fA;
GN   Name=insF6; Synonyms=yaaB; OrderedLocusNames=ECOK12F002;
OS   Escherichia coli (strain K12).
OG   Plasmid F.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / CR63; PLASMID=F;
RA   Shimizu H., Saitoh Y., Suda Y., Uehara K., Sampei G., Mizobuchi K.;
RT   "Complete nucleotide sequence of the F plasmid: its implications for
RT   organization and diversification of plasmid genomes.";
RL   Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence IS3.
CC   -!- SIMILARITY: Belongs to the transposase IS3/IS150/IS904 family.
CC       {ECO:0000305}.
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DR   EMBL; AP001918; BAA97872.1; -; Genomic_DNA.
DR   RefSeq; NP_061381.1; NC_002483.1.
DR   RefSeq; WP_000878218.1; NZ_CP011343.2.
DR   AlphaFoldDB; P0CF84; -.
DR   PATRIC; fig|1411691.4.peg.161; -.
DR   OMA; CARYNTT; -.
DR   PhylomeDB; P0CF84; -.
DR   PRO; PR:P0CF84; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR025948; HTH-like_dom.
DR   InterPro; IPR038965; InsF-like.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR46889:SF1; PTHR46889:SF1; 1.
DR   Pfam; PF13276; HTH_21; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF13333; rve_2; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Plasmid; Transposable element;
KW   Transposition.
FT   CHAIN           1..288
FT                   /note="Transposase InsF for insertion sequence IS3fA"
FT                   /id="PRO_0000394038"
FT   DOMAIN          124..287
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
SQ   SEQUENCE   288 AA;  33540 MW;  9237EA662E021EB4 CRC64;
     MKYVFIEKHQ AEFSIKAMCR VLRVARSGWY TWCQRRTRIS TRQQFRQHCD SVVLAAFTRS
     KQRYGAPRLT DELRAQGYPF NVKTVAASLR RQGLRAKASR KFSPVSYRAH GLPVSENLLE
     QDFYASGPNQ KWAGDITYLR TDEGWLYLAV VIDLWSRAVI GWSMSPRMTA QLACDALQMA
     LWRRKRPRNV IVHTDRGGQY CSADYQAQLK RHNLRGSMSA KGCCYDNACV ESFFHSLKVE
     CIHGEHFISR EIMRATVFNY IECDYNRWRR HSWCGGLSPE QFENKNLA