ID   INSD_ECOLX              Reviewed;         301 AA.
AC   P0C5W5; P19777; P76167; P76916; P77033; Q79EJ0;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Transposase InsD for insertion element IS2A/D/F/H/I/K;
GN   Name=insD;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33694 / HB101;
RX   PubMed=2830172; DOI=10.1016/0378-1119(87)90337-4;
RA   Ronecker H.J., Rak B.;
RT   "Genetic organization of insertion element IS2 based on a revised
RT   nucleotide sequence.";
RL   Gene 59:291-296(1987).
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence IS2.
CC       {ECO:0000250}.
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DR   EMBL; V00279; CAA23541.1; -; Genomic_DNA.
DR   PIR; A64764; C65092.
DR   RefSeq; WP_000376502.1; NC_007635.1.
DR   RefSeq; YP_424823.1; NC_007635.1.
DR   AlphaFoldDB; P0C5W5; -.
DR   IntAct; P0C5W5; 2.
DR   OMA; PRRTMYY; -.
DR   OrthoDB; 1637053at2; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR025948; HTH-like_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF13276; HTH_21; 1.
DR   Pfam; PF00665; rve; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transposable element; Transposition.
FT   CHAIN           1..301
FT                   /note="Transposase InsD for insertion element
FT                   IS2A/D/F/H/I/K"
FT                   /id="PRO_0000311588"
FT   DOMAIN          106..289
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
SQ   SEQUENCE   301 AA;  34398 MW;  9D6E3EB8FA7E2BA5 CRC64;
     MDSARALIAR GWGVSLVSRC LRVSRAQLHV ILRRTDDWMD GRRSRHTDDT DVLLRIHHVI
     GELPTYGYRR VWALLRRQAE LDGMPAINAK RVYRIMRQNA LLLERKPAVP PSKRAHTGRV
     AVKESNQRWC SDGFEFCCDN GERLRVTFAL DCCDREALHW AVTTGGFNSE TVQDVMLGAV
     ERRFGNDLPS SPVEWLTDNG SCYRANETRQ FARMLGLEPK NTAVRSPESN GIAESFVKTI
     KRDYISIMPK PDGLTAAKNL AEAFEHYNEW HPHSALGYRS PREYLRQRAC NGLSDNRCLE
     I