ID   INH18_ECOLI             Reviewed;         326 AA.
AC   P0CE65; O07987; O07988; P03837; P76355; Q2MBK1; Q2MBM8;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   23-MAR-2010, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Transposase InsH for insertion sequence element IS5-18;
GN   OrderedLocusNames=JW5951;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA   Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA   Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA   Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA   Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA   Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA   Horiuchi T.;
RT   "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 40.1-50.0 min region on the linkage map.";
RL   DNA Res. 3:379-392(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence IS5.
CC   -!- SIMILARITY: Belongs to the transposase 11 family. {ECO:0000305}.
CC   -!- CAUTION: There is no equivalent of this gene in strain K12 / MG1655.
CC       {ECO:0000305}.
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DR   EMBL; AP009048; BAE78086.1; -; Genomic_DNA.
DR   AlphaFoldDB; P0CE65; -.
DR   PRIDE; P0CE65; -.
DR   EnsemblBacteria; BAE78086; BAE78086; BAE78086.
DR   KEGG; ecj:JW5951; -.
DR   PATRIC; fig|83333.103.peg.1012; -.
DR   HOGENOM; CLU_049873_1_2_6; -.
DR   PhylomeDB; P0CE65; -.
DR   PRO; PR:P0CE65; -.
DR   Proteomes; UP000000318; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   InterPro; IPR002559; Transposase_11.
DR   InterPro; IPR008490; Transposase_InsH_N.
DR   Pfam; PF01609; DDE_Tnp_1; 1.
DR   Pfam; PF05598; DUF772; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transposable element; Transposition.
FT   CHAIN           1..326
FT                   /note="Transposase InsH for insertion sequence element IS5-
FT                   18"
FT                   /id="PRO_0000392496"
SQ   SEQUENCE   326 AA;  37851 MW;  07FD70483E9E922E CRC64;
     MSHQLTFADS EFSSKRRQTR KEIFLSRMEQ ILPWQNMVEV IEPFYPKAGN GRRPYPLETM
     LRIHCMQHWY NLSDGAMEDA LYEIASMRLF ARLSLDSALP DRTTIMNFRH LLEQHQLARQ
     LFKTINRWLA EAGVMMTQGT LVDATIIEAP SSTKNKEQQR DPEMHQTKKG NQWHFGMKAH
     IGVDAKSGLT HSLVTTAANE HDLNQLGNLL HGEEQFVSAD AGYQGAPQRE ELAEVDVDWL
     IAERPGKVRT LKQHPRKNKT AINIEYMKAS IRARVEHPFR IIKRQFGFVK ARYKGLLKND
     NQLAMLFTLA NLFRADQMIR QWERSH