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HVM02_MOUSE
ID   HVM02_MOUSE             Reviewed;         140 AA.
AC   P01746;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Ig heavy chain V region 93G7;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=A/J;
RX   PubMed=6801765; DOI=10.1126/science.6801765;
RA   Sims J., Rabbitts T.H., Estess P., Slaughter C., Tucker P.W., Capra J.D.;
RT   "Somatic mutation in genes for the variable portion of the immunoglobulin
RT   heavy chain.";
RL   Science 216:309-311(1982).
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DR   EMBL; J00493; AAA38128.1; -; mRNA.
DR   PIR; PH1482; PH1482.
DR   PIR; PH1490; PH1490.
DR   PIR; PH1491; PH1491.
DR   PIR; PH1500; PH1500.
DR   PIR; PH1504; PH1504.
DR   PIR; PH1512; PH1512.
DR   PIR; PH1518; PH1518.
DR   PIR; PH1520; PH1520.
DR   PIR; PH1521; PH1521.
DR   PIR; PH1522; PH1522.
DR   PIR; PH1523; PH1523.
DR   AlphaFoldDB; P01746; -.
DR   SMR; P01746; -.
DR   MINT; P01746; -.
DR   MaxQB; P01746; -.
DR   PeptideAtlas; P01746; -.
DR   PRIDE; P01746; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01746; protein.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR   GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR   GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR   GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   2: Evidence at transcript level;
KW   Adaptive immunity; Hybridoma; Immunity; Immunoglobulin; Reference proteome;
KW   Signal.
FT   SIGNAL          1..19
FT   CHAIN           20..140
FT                   /note="Ig heavy chain V region 93G7"
FT                   /id="PRO_0000015216"
FT   DOMAIN          20..139
FT                   /note="Ig-like"
FT   NON_TER         140
SQ   SEQUENCE   140 AA;  15514 MW;  25A4CBBE31DA5CE8 CRC64;
     MGWSFIFLFL LSVTAGVHSE VQLQQSGAEL VRAGSSVKMS CKASGYTFTS YGINWVKQRP
     GQGLEWIGYI NPGNGYINYN EKFKGKTTLT VDKSSSTAYM QLRSLTSEDS AVYFCARSHY
     YGGSYDFDYW GQGTPLTVSS
 
 
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