HVM01_MOUSE
ID HVM01_MOUSE Reviewed; 121 AA.
AC P01745;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Ig heavy chain V region MPC 11;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=6253904; DOI=10.1093/nar/8.16.3591;
RA Zakut R., Cohen J., Givol D.;
RT "Cloning and sequence of the cDNA corresponding to the variable region of
RT immunoglobulin heavy chain MPC11.";
RL Nucleic Acids Res. 8:3591-3601(1980).
RN [2]
RP ERRATUM OF PUBMED:6253904, AND SEQUENCE REVISION.
RA Zakut R., Cohen J., Givol D.;
RL Nucleic Acids Res. 8:4839-4840(1980).
CC -!- MISCELLANEOUS: This sequence was translated from an mRNA isolated from
CC a myeloma that secretes IgG2b.
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DR PIR; A93708; GVMS11.
DR AlphaFoldDB; P01745; -.
DR SMR; P01745; -.
DR PRIDE; P01745; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01745; protein.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Adaptive immunity; Immunity; Immunoglobulin; Reference proteome.
FT CHAIN 1..>121
FT /note="Ig heavy chain V region MPC 11"
FT /id="PRO_0000059868"
FT DOMAIN 1..112
FT /note="Ig-like"
FT NON_TER 121
SQ SEQUENCE 121 AA; 13135 MW; 227AEF3EC56ED0BF CRC64;
EAQLQQSGAE LVRPGTSVKI SCKAAGYTFT NYWIGWVKER PGHGLEWIGD IYPGGGFTNY
NDNLKGKATL TADTSSSTAY IQLSSLTSED SAIYHCARGI YYNSSPYFDS WGQGTTLTVS
S