ID   HVCS_HETFR              Reviewed;         438 AA.
AC   P23087;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Ig heavy chain C region, secreted form;
DE   AltName: Full=Clone 3050;
DE   Flags: Fragment;
OS   Heterodontus francisci (Horn shark) (Cestracion francisci).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Heterodontoidea; Heterodontiformes;
OC   Heterodontidae; Heterodontus.
OX   NCBI_TaxID=7792;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Spleen;
RX   PubMed=3138109; DOI=10.1002/j.1460-2075.1988.tb03036.x;
RA   Kokubu F., Hinds K., Litman R., Shamblott M.J., Litman G.W.;
RT   "Complete structure and organization of immunoglobulin heavy chain constant
RT   region genes in a phylogenetically primitive vertebrate.";
RL   EMBO J. 7:1979-1988(1988).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA30613.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X07781; CAA30613.1; ALT_INIT; Genomic_DNA.
DR   PIR; D32716; D32716.
DR   PIR; S01853; HVRKCS.
DR   AlphaFoldDB; P23087; -.
DR   SMR; P23087; -.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 4.
DR   SMART; SM00407; IGc1; 4.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 4.
DR   PROSITE; PS00290; IG_MHC; 3.
PE   4: Predicted;
KW   Glycoprotein; Immunoglobulin domain.
FT   CHAIN           <1..438
FT                   /note="Ig heavy chain C region, secreted form"
FT                   /id="PRO_0000153632"
FT   REGION          1..99
FT                   /note="CH1"
FT   REGION          100..205
FT                   /note="CH2"
FT   REGION          206..308
FT                   /note="CH3"
FT   REGION          309..418
FT                   /note="CH4"
FT   CARBOHYD        164
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        200
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        245
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        275
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        374
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        411
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        415
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        425
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
SQ   SEQUENCE   438 AA;  47920 MW;  9BDF37C3BBD7D15B CRC64;
     ATPSPPTLYG LCSCEQPNTD GSLAYGCLAM DYIPQITSVS WKKDNEPITT GLKTYPSVLN
     KKGTYTQSSQ LTITESEVGS SKIYCEVRRG ESVWIKEIPD CKGDKVHPTV ILTQSSSEEI
     TSRRFATVLC SIIDFHPESI TVSWLKDGQH MESGFVTSPT CGVNGTFSAT SRLTVPAREW
     FTNKVYTCQV SHQGVTQSRN ITGSQVPCSC NDPVIKLLPP SIEQVLLEAT VTLTCVVSNA
     PYGVNVSWTQ EQKSLKSEIA VQPGEDADSV ISTVNISTQA WLSGAEFYCV VNHQDLPTPL
     RASIHKEEVK DLREPSVSIL LSPAEDVSAQ RFLSLTCLVR GFFPREIFVK WTVNDKSVNP
     GNYKNTEVMA ENDNSSYFIY SLLSIAAEEW ASGASYSCVV GHEAIPLKII NRTVNKSSGK
     PSFVNISLAL LDTVNSCQ