ID   HSP70_BRELC             Reviewed;         676 AA.
AC   P16394;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Heat shock 70 kDa protein;
GN   Name=HSP70;
OS   Bremia lactucae (Lettuce downy mildew).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Bremia.
OX   NCBI_TaxID=4779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2792764; DOI=10.1016/0378-1119(89)90203-5;
RA   Judelson H.S., Michelmore R.W.;
RT   "Structure and expression of a gene encoding heat-shock protein Hsp70 from
RT   the Oomycete fungus Bremia lactucae.";
RL   Gene 79:207-217(1989).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; M27825; AAA33009.1; -; Genomic_DNA.
DR   PIR; JU0062; HHUM7B.
DR   AlphaFoldDB; P16394; -.
DR   SMR; P16394; -.
DR   PRIDE; P16394; -.
DR   VEuPathDB; FungiDB:CCR75_001741; -.
DR   VEuPathDB; FungiDB:CCR75_006137; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Stress response.
FT   CHAIN           1..676
FT                   /note="Heat shock 70 kDa protein"
FT                   /id="PRO_0000078363"
FT   REGION          657..676
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   676 AA;  74088 MW;  9907150B7C386730 CRC64;
     MAQSVSGYSV GIDLGTTYSC VGVWQNDRVE IIANDQGNRT TPSYVAFTDT ERLIGDAAKN
     QVAMNAHNTV FDAKPLIGRK FSDPIVQADI KHWPFKLTSG WRQAQIVVQF KGESKTFQPE
     EISSMVLIKM REVAEAFIGK EVKNAVITVP AYFNDSQRQA TKDAGAIAGL NVLRIINEPT
     AAAIAYGLDK KGGERNVLIF DLGGGTFDVS LLSIEEGIFE VKSTARDTHL GGEDFDNRLV
     DHFTQEFKRK HRKDITENQR ALRRLRTACE RAKRTLSSSA QAYIEIDSLF DGIDFNSTIT
     RARFEDMCGD YFRKTMEPVA PVLRDAKLSK SQVHEVVLVG GSTRIPKVQQ LLSDFFNGKE
     PNKSINPDEP VAYGATVQAA ILSGNDSSQK LQDLLLLDVT PLSLGLETAG GVMTTLIARN
     TTVPTKKSQT FSTYADNQPG VLIQLFEGER SMTRDNNLLG KFNLDGIPPM PRGVPQIDVT
     FDIDANGIFN VSAVEKSTGK ENKITITNDR VVCRRHDIDR MVSEAEKYKS EDEANKIRIE
     AKNGLENYSY NLRNTLNDEK LKDQIPEDDK KAIEDKVTET INWLDANQSA EKEEYEGKQK
     ELEGIANPIL QKMYAAAGAA GGMPGGMPGM PGGMPGMPGG MPGMPGGMPG GMPGGMPGGW
     PPCWSSDQGP KIEEVD