ID   HSP41_PEA               Reviewed;         197 AA.
AC   P19244;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=22.7 kDa class IV heat shock protein;
DE   Flags: Precursor;
GN   Name=HSP22.7;
OS   Pisum sativum (Garden pea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Fabeae; Pisum.
OX   NCBI_TaxID=3888;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2377479; DOI=10.1093/nar/18.14.4274;
RA   Lauzon L.M., Helm K.W., Vierling E.;
RT   "A cDNA clone from Pisum sativum encoding a low molecular weight heat shock
RT   protein.";
RL   Nucleic Acids Res. 18:4274-4274(1990).
RN   [2]
RP   SUBCELLULAR LOCATION.
RX   PubMed=8417329; DOI=10.1128/mcb.13.1.238-247.1993;
RA   Helm K.W., Lafayette P.R., Nagao R.T., Key J.L., Vierling E.;
RT   "Localization of small heat shock proteins to the higher plant endomembrane
RT   system.";
RL   Mol. Cell. Biol. 13:238-247(1993).
CC   -!- SUBUNIT: Forms oligomeric structures.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen
CC       {ECO:0000305|PubMed:8417329}. Note=In the endomembrane, probably in the
CC       lumen of endoplasmic reticulum.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR   EMBL; M33898; AAA33673.1; -; mRNA.
DR   PIR; A48113; A48113.
DR   AlphaFoldDB; P19244; -.
DR   SMR; P19244; -.
DR   GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR   GO; GO:0009408; P:response to heat; IEA:EnsemblPlants.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR007052; CS_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Signal; Stress response.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..197
FT                   /note="22.7 kDa class IV heat shock protein"
FT                   /id="PRO_0000013526"
FT   DOMAIN          68..184
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT   MOTIF           194..197
FT                   /note="Prevents secretion from ER"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   197 AA;  22734 MW;  D8668F41BBDF6BE5 CRC64;
     MSLKPLNMLL VPFLLLILAA DFPLKAKASL LPFIDSPNTL LSDLWSDRFP DPFRVLEQIP
     YGVEKHEPSI TLSHARVDWK ETPEGHVIMV DVPGLKKDDI KIEVEENRVL RVSGERKKEE
     DKKGDHWHRV ERSYGKFWRQ FKLPQNVDLD SVKAKMENGV LTLTLHKLSH DKIKGPRMVS
     IVEEDDKPSK IVNDELK