ID   AP5B1_XENTR             Reviewed;         883 AA.
AC   F6S215;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=AP-5 complex subunit beta-1;
DE   AltName: Full=Adaptor-related protein complex 5 beta subunit;
DE            Short=Beta5;
GN   Name=ap5b1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20431018; DOI=10.1126/science.1183670;
RA   Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA   Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA   Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA   Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA   Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA   Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA   Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA   Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA   Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT   "The genome of the Western clawed frog Xenopus tropicalis.";
RL   Science 328:633-636(2010).
CC   -!- FUNCTION: As part of AP-5, a probable fifth adaptor protein complex, it
CC       may be involved in endosomal transport. {ECO:0000250}.
CC   -!- SUBUNIT: Probably part of the adaptor protein complex 5 (AP-5).
CC       {ECO:0000250}.
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DR   EMBL; AAMC01065270; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; F6S215; -.
DR   SMR; F6S215; -.
DR   STRING; 8364.ENSXETP00000058924; -.
DR   PaxDb; F6S215; -.
DR   eggNOG; ENOG502QVTX; Eukaryota.
DR   InParanoid; F6S215; -.
DR   OMA; VWCPLGP; -.
DR   TreeFam; TF332158; -.
DR   Proteomes; UP000008143; Genome assembly.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0030119; C:AP-type membrane coat adaptor complex; ISS:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR038741; AP5B1.
DR   InterPro; IPR011989; ARM-like.
DR   PANTHER; PTHR34033; PTHR34033; 2.
PE   3: Inferred from homology;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..883
FT                   /note="AP-5 complex subunit beta-1"
FT                   /id="PRO_0000417048"
SQ   SEQUENCE   883 AA;  100976 MW;  1BBC8B2740C1454F CRC64;
     MAERNSASWN RKVASFCSEP KTFLCDSSVD GFLGELLKDL QSEAIHGQTK ILMMDLLLEF
     PEFLCPDQKT VEMTAETLMN ILKKMPSSER SMTLRCHLLL AIETVLITCE SFNQNSKMAQ
     DFASLLMHII SDVNDKKQGV ANRPLRTTAC ECLRELESCY PGFLSQRMEK LYLMQQQEVT
     AAHQSYTLLY TVVLKNAIRF LAQKEGPSNG ALKNALLSNE DFFWSATENM VELQPSSNEQ
     LLLLPSNSET KDLKSILALL LEDSYLLTPV CQNTLFWQIV QVVAMARTIS PVIFKSQLVR
     LFSTMDLSCF HSILQMKAVF TDSLFTGEDE HFLIQRLVGM TQHPLLSTPV KLFYLDCLLH
     FPENRPLTSN SEENLPVLLT VQMTSSLFPN VFNDHSTMLC RQNVLSMVYL ENEGSYSEKG
     IAFLFEHVMS LYSMVHKNGN REITATFFRA VHLFVQYFNF CEKHMENLTE KLLKLYMSNS
     SLAPNFINLI NQTQILLEFH VWPVTLSKAL QKEIVNLPTD KWTMKNLGWH LKILSRVAQE
     NSISQSSTAL FLRRVVFCSD LCSKGDWRTG NALLSVCKHV LQHQKLSAIF VHLADLLQYL
     MHRFEDIDVQ DRARLYYVLL TNVSSDKLGK ILTMSPARGQ TKSRSLSSIM TENENFSTML
     TIRNAEKTLL CLQPVLEGIK AFTCISDSPS LYCIVLQFEN TDCRFESISD INVPCLFVDR
     KPPVVTINLV PKEPYPTIFS VSATYSTQDG ITYQTKLDPL YITFREMFIP LPLPALWPLE
     SRFDLFGKLW SAFKPDEQNQ FEESIFCYEM SNNSLHDIVL DNFSKFAVSC NGGEYKIAVF
     LPPQFHILMH IKSQDDTACF SVRTDNWNLL PYLNSHLLDI TLQ