HPR_BACVZ
ID HPR_BACVZ Reviewed; 203 AA.
AC A7Z311;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=HTH-type transcriptional regulator Hpr {ECO:0000255|HAMAP-Rule:MF_01911};
DE AltName: Full=Protease production regulatory protein Hpr {ECO:0000255|HAMAP-Rule:MF_01911};
GN Name=hpr {ECO:0000255|HAMAP-Rule:MF_01911}; OrderedLocusNames=RBAM_010230;
OS Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)
OS (Bacillus amyloliquefaciens subsp. plantarum).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus amyloliquefaciens group.
OX NCBI_TaxID=326423;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42;
RX PubMed=17704766; DOI=10.1038/nbt1325;
RA Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K.,
RA Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H.,
RA Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H.,
RA Strittmatter A., Gottschalk G., Borriss R.;
RT "Comparative analysis of the complete genome sequence of the plant growth-
RT promoting bacterium Bacillus amyloliquefaciens FZB42.";
RL Nat. Biotechnol. 25:1007-1014(2007).
CC -!- FUNCTION: Negative regulator of protease production and sporulation.
CC {ECO:0000255|HAMAP-Rule:MF_01911}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01911}.
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DR EMBL; CP000560; ABS73387.1; -; Genomic_DNA.
DR RefSeq; WP_003155240.1; NC_009725.2.
DR AlphaFoldDB; A7Z311; -.
DR SMR; A7Z311; -.
DR STRING; 326423.RBAM_010230; -.
DR EnsemblBacteria; ABS73387; ABS73387; RBAM_010230.
DR GeneID; 66327026; -.
DR KEGG; bay:RBAM_010230; -.
DR HOGENOM; CLU_115790_0_0_9; -.
DR OMA; EKDWQNW; -.
DR Proteomes; UP000001120; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; -; 1.
DR HAMAP; MF_01911; HTH_type_Hpr; 1.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR023488; HTH_tscrpt_reg_Hpr.
DR InterPro; IPR023187; Tscrpt_reg_MarR-type_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF01047; MarR; 1.
DR SMART; SM00347; HTH_MARR; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS01117; HTH_MARR_1; 1.
DR PROSITE; PS50995; HTH_MARR_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Repressor; Sporulation; Transcription;
KW Transcription regulation.
FT CHAIN 1..203
FT /note="HTH-type transcriptional regulator Hpr"
FT /id="PRO_0000343616"
FT DOMAIN 13..157
FT /note="HTH marR-type"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01911"
FT DNA_BIND 63..86
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01911"
FT REGION 178..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 203 AA; 23847 MW; 374566559F491F01 CRC64;
MNRVEPPYDL KEALIYTQKM AQLSKALWKS IEKDWQNWLK PYDLNINEHH ILWIAYQLKG
ASISEIAKFG VMHVSTAFNF SKKLEERGYL KFSKRLNDKR NTYIQLTEEG ENVFESLLEE
FDPSRNAVFK GSQPIYHLFG KFPEVEELTC VIRHIYGEDF MEIFEKSLTN INNDFDSEDG
RLKKKTDESA VHETAEELEP INS
