ID   HNRDL_CHICK             Reviewed;         301 AA.
AC   Q5ZI72;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein D-like;
DE            Short=hnRNP D-like;
DE            Short=hnRNP DL;
GN   Name=HNRNPDL; Synonyms=HNRPDL; ORFNames=RCJMB04_29l7;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Acts as a transcriptional regulator. Binds DNA and RNA (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O14979}. Cytoplasm
CC       {ECO:0000250|UniProtKB:O14979}. Note=Shuttles between the nucleus and
CC       the cytoplasm in a TNPO1-dependent manner.
CC       {ECO:0000250|UniProtKB:O14979}.
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DR   EMBL; AJ720912; CAG32571.1; -; mRNA.
DR   RefSeq; NP_001026313.1; NM_001031142.1.
DR   RefSeq; XP_015131753.1; XM_015276267.1.
DR   AlphaFoldDB; Q5ZI72; -.
DR   SMR; Q5ZI72; -.
DR   BioGRID; 683263; 1.
DR   STRING; 9031.ENSGALP00000037222; -.
DR   PaxDb; Q5ZI72; -.
DR   Ensembl; ENSGALT00000038016; ENSGALP00000037222; ENSGALG00000023199.
DR   Ensembl; ENSGALT00000047514; ENSGALP00000055771; ENSGALG00000023199.
DR   Ensembl; ENSGALT00000068418; ENSGALP00000052960; ENSGALG00000023199.
DR   GeneID; 422601; -.
DR   KEGG; gga:422601; -.
DR   CTD; 9987; -.
DR   VEuPathDB; HostDB:geneid_422601; -.
DR   eggNOG; KOG0118; Eukaryota.
DR   GeneTree; ENSGT00940000154426; -.
DR   HOGENOM; CLU_012062_1_1_1; -.
DR   InParanoid; Q5ZI72; -.
DR   OMA; RSFNDGF; -.
DR   OrthoDB; 1565323at2759; -.
DR   PhylomeDB; Q5ZI72; -.
DR   PRO; PR:Q5ZI72; -.
DR   Proteomes; UP000000539; Chromosome 4.
DR   Bgee; ENSGALG00000023199; Expressed in ovary and 13 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008143; F:poly(A) binding; IBA:GO_Central.
DR   GO; GO:0034046; F:poly(G) binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   CDD; cd12758; RRM1_hnRPDL; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR034847; hnRPDL_RRM1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   Cytoplasm; DNA-binding; Methylation; Nucleus; Reference proteome; Repeat;
KW   RNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..301
FT                   /note="Heterogeneous nuclear ribonucleoprotein D-like"
FT                   /id="PRO_0000287242"
FT   DOMAIN          30..112
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          115..194
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          194..230
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..209
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..301
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   301 AA;  33444 MW;  DAA3E50207FE26C0 CRC64;
     MEDATEMSGG AEEFAEGSKI NASKNQQDDG KMFIGGLSWD TSKKDLTEYL SRFGEVVDCT
     IKTDPVTGRS RGFGFVLFKD AASVEKVLEL KEHKLDGKLI DPKRAKALKG KEPPKKVFVG
     GLSPDTSEEQ IKEYFGAFGE IENIELPMDT KTNERRGFCF ITYTDEEPVK KLLESRYHQI
     GSGKCEIKVA QPKEVYRQQQ QQQKGGKSNA SGGRGGGRGR GRGQGQNWNQ GFNNYYDQGY
     GNYNSAYSDQ SYSGYGGYDY SGYNYPNYGY GPGYTDYSGQ QSTYGKASRG GGNHQNNYQP
     Y