ID   HISP_PSEAE              Reviewed;         255 AA.
AC   Q9HZS1;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Histidine transport ATP-binding protein HisP;
GN   Name=hisP; OrderedLocusNames=PA2926;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Part of the histidine permease ABC transporter. Responsible
CC       for energy coupling to the transport system (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HisP),
CC       two transmembrane proteins (HisM and HisQ) and a solute-binding protein
CC       (HisJ). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Peripheral
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; AE004091; AAG06314.1; -; Genomic_DNA.
DR   PIR; D83281; D83281.
DR   RefSeq; NP_251616.1; NC_002516.2.
DR   RefSeq; WP_003114012.1; NZ_QZGE01000009.1.
DR   AlphaFoldDB; Q9HZS1; -.
DR   SMR; Q9HZS1; -.
DR   STRING; 287.DR97_5015; -.
DR   PaxDb; Q9HZS1; -.
DR   PRIDE; Q9HZS1; -.
DR   EnsemblBacteria; AAG06314; AAG06314; PA2926.
DR   GeneID; 882578; -.
DR   KEGG; pae:PA2926; -.
DR   PATRIC; fig|208964.12.peg.3067; -.
DR   PseudoCAP; PA2926; -.
DR   HOGENOM; CLU_000604_1_22_6; -.
DR   InParanoid; Q9HZS1; -.
DR   OMA; NITMAPR; -.
DR   PhylomeDB; Q9HZS1; -.
DR   BioCyc; PAER208964:G1FZ6-2976-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015424; F:ABC-type amino acid transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR030679; ABC_ATPase_HisP-typ.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   PIRSF; PIRSF039085; ABC_ATPase_HisP; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; ATP-binding; Cell inner membrane; Cell membrane;
KW   Membrane; Nucleotide-binding; Reference proteome; Transport.
FT   CHAIN           1..255
FT                   /note="Histidine transport ATP-binding protein HisP"
FT                   /id="PRO_0000287736"
FT   DOMAIN          4..250
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   255 AA;  28518 MW;  3B8F587FCD91892B CRC64;
     MYSLQVEDIH KRYGSHEVLR GVSLRAGKGD VISIIGSSGS GKSTFLRCVN FLEKPCAGHI
     RVGDEELRTR PGALGELRAA DPRQLQRIRS RLAMVFQHFN LWSHLTVLEN VVECPVNVLR
     MNRDDAVARA RHYLAKVGLA EKVERQYPCE LSGGQQQRVA IARALAMEPQ VMLFDEPTSA
     LDPELVGEVL KVMQQLAEEG RTMVLVTHEM AFARQVSSHV IFLHQGVIEE EGTPDQVFGA
     PRSERLRQFL AGNLK