ID   HCT2_CHLT2              Reviewed;         221 AA.
AC   Q46397; B0B9F4;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Histone H1-like protein HC2;
DE   AltName: Full=HC2 nucleoprotein;
GN   Name=hctB; Synonyms=hct2; OrderedLocusNames=CTL0302;
OS   Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=471472;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7687246; DOI=10.1128/jb.175.14.4274-4281.1993;
RA   Brickman T.J., Barry C.E. III, Hackstadt T.W.;
RT   "Molecular cloning and expression of hctB encoding a strain-variant
RT   chlamydial histone-like protein with DNA-binding activity.";
RL   J. Bacteriol. 175:4274-4281(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=434/Bu / ATCC VR-902B;
RX   PubMed=18032721; DOI=10.1101/gr.7020108;
RA   Thomson N.R., Holden M.T.G., Carder C., Lennard N., Lockey S.J., Marsh P.,
RA   Skipp P., O'Connor C.D., Goodhead I., Norbertzcak H., Harris B., Ormond D.,
RA   Rance R., Quail M.A., Parkhill J., Stephens R.S., Clarke I.N.;
RT   "Chlamydia trachomatis: genome sequence analysis of lymphogranuloma
RT   venereum isolates.";
RL   Genome Res. 18:161-171(2008).
CC   -!- FUNCTION: Might have a role in establishing the nucleoid structure of
CC       elementary bodies.
CC   -!- DEVELOPMENTAL STAGE: Specific to the EB (elementary body) form in the
CC       life cycle of chlamydiae.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. HCT subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAP03741.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L10193; AAA23130.1; -; Genomic_DNA.
DR   EMBL; AM884176; CAP03741.1; ALT_INIT; Genomic_DNA.
DR   PIR; A36884; A36884.
DR   RefSeq; WP_009873517.1; NC_010287.1.
DR   RefSeq; YP_001654385.1; NC_010287.1.
DR   AlphaFoldDB; Q46397; -.
DR   EnsemblBacteria; CAP03741; CAP03741; CTL0302.
DR   KEGG; ctb:CTL0302; -.
DR   PATRIC; fig|471472.4.peg.327; -.
DR   HOGENOM; CLU_101293_0_0_0; -.
DR   OMA; CKRVCSS; -.
DR   Proteomes; UP000000795; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR   InterPro; IPR009970; HC2.
DR   Pfam; PF07382; HC2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Repeat.
FT   CHAIN           1..221
FT                   /note="Histone H1-like protein HC2"
FT                   /id="PRO_0000196024"
FT   REGION          1..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..70
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   221 AA;  23549 MW;  DCDCEAD5404EEA94 CRC64;
     MLGVQKKRST RKTAARKTVV RKPAAKKTAA KKAPVRKVAA KKTVARKTVA KKTVAARKPV
     AKKATAKKAP VRKAVAKKTV ARKTVAKKTV AARKPVAKKA TAKKAPVRKV AAKKTVARKT
     VAKKTVAARK PVAKKATAKK APVRKAVAKK TVAKRVASTK KSSVAVKAGV CMKKHKHTAA
     CGRVAASGVK VCASAAKRKM NPNRSRTAHS WRQQLMKLVA R