HAT9_ARATH
ID HAT9_ARATH Reviewed; 274 AA.
AC P46603; O82763; Q0WP63;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 27-MAY-2002, sequence version 2.
DT 03-AUG-2022, entry version 149.
DE RecName: Full=Homeobox-leucine zipper protein HAT9;
DE AltName: Full=Homeodomain-leucine zipper protein HAT9;
DE Short=HD-ZIP protein 9;
GN Name=HAT9; OrderedLocusNames=At2g22800; ORFNames=T20K9.1, T30L20.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=7915839; DOI=10.1073/pnas.91.18.8393;
RA Schena M., Davis R.W.;
RT "Structure of homeobox-leucine zipper genes suggests a model for the
RT evolution of gene families.";
RL Proc. Natl. Acad. Sci. U.S.A. 91:8393-8397(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Sessa G., Carabelli M., Ciarbelli A.R., Ruzza V., Steindler C., Ruberti I.;
RT "Nucleotide sequence of the Arabidopsis HAT9 mRNA, encoding an HD-Zip II
RT protein related to ATHB-2.";
RL Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY.
RX PubMed=16055682; DOI=10.1104/pp.105.063461;
RA Henriksson E., Olsson A.S.B., Johannesson H., Johansson H., Hanson J.,
RA Engstroem P., Soederman E.;
RT "Homeodomain leucine zipper class I genes in Arabidopsis. Expression
RT patterns and phylogenetic relationships.";
RL Plant Physiol. 139:509-518(2005).
CC -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC -!- INTERACTION:
CC P46603; Q8GXM7: ATHB-X; NbExp=4; IntAct=EBI-15192157, EBI-3133795;
CC P46603; P46600: HAT1; NbExp=4; IntAct=EBI-15192157, EBI-15195911;
CC P46603; Q8LAV5: REM20; NbExp=3; IntAct=EBI-15192157, EBI-15192159;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class II subfamily.
CC {ECO:0000305}.
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DR EMBL; U09341; AAA56907.1; -; mRNA.
DR EMBL; U09342; AAA56908.1; -; mRNA.
DR EMBL; AJ441253; CAD29652.1; -; mRNA.
DR EMBL; AC004786; AAC32427.1; -; Genomic_DNA.
DR EMBL; AC005617; AAM15064.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07356.1; -; Genomic_DNA.
DR EMBL; AK229218; BAF01086.1; -; mRNA.
DR PIR; A84617; A84617.
DR PIR; T52371; T52371.
DR PIR; T52372; T52372.
DR RefSeq; NP_179865.1; NM_127845.4.
DR AlphaFoldDB; P46603; -.
DR SMR; P46603; -.
DR BioGRID; 2164; 17.
DR IntAct; P46603; 16.
DR STRING; 3702.AT2G22800.1; -.
DR PaxDb; P46603; -.
DR PRIDE; P46603; -.
DR ProteomicsDB; 230285; -.
DR EnsemblPlants; AT2G22800.1; AT2G22800.1; AT2G22800.
DR GeneID; 816811; -.
DR Gramene; AT2G22800.1; AT2G22800.1; AT2G22800.
DR KEGG; ath:AT2G22800; -.
DR Araport; AT2G22800; -.
DR TAIR; locus:2059143; AT2G22800.
DR eggNOG; KOG0483; Eukaryota.
DR HOGENOM; CLU_049516_0_0_1; -.
DR InParanoid; P46603; -.
DR OMA; LYMHMPA; -.
DR OrthoDB; 1333079at2759; -.
DR PhylomeDB; P46603; -.
DR PRO; PR:P46603; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; P46603; baseline and differential.
DR Genevisible; P46603; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR003106; Leu_zip_homeo.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00340; HALZ; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..274
FT /note="Homeobox-leucine zipper protein HAT9"
FT /id="PRO_0000048904"
FT DNA_BIND 110..169
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 64..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..198
FT /note="Leucine-zipper"
FT CONFLICT 21
FT /note="P -> S (in Ref. 1; AAA56907/AAA56908 and 2;
FT CAD29652)"
FT /evidence="ECO:0000305"
FT CONFLICT 90
FT /note="E -> V (in Ref. 1; AAA56908)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 274 AA; 29878 MW; 3587F38B0855F405 CRC64;
MGFDDTCNTG LVLGLGPSPI PNNYNSTIRQ SSVYKLEPSL TLCLSGDPSV TVVTGADQLC
RQTSSHSGVS SFSSGRVVKR ERDGGEESPE EEEMTERVIS DYHEDEEGIS ARKKLRLTKQ
QSALLEESFK DHSTLNPKQK QVLARQLNLR PRQVEVWFQN RRARTKLKQT EVDCEFLKKC
CETLADENIR LQKEIQELKT LKLTQPFYMH MPASTLTKCP SCERIGGGGG GNGGGGGGSG
ATAVIVDGST AKGAFSISSK PHFFNPFTNP SAAC
