HAT1_ORYSJ
ID HAT1_ORYSJ Reviewed; 466 AA.
AC Q6ES10; Q0J2F5;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Probable histone acetyltransferase type B catalytic subunit;
DE EC=2.3.1.48 {ECO:0000250|UniProtKB:O14929};
DE AltName: Full=HAT B;
GN Name=HATB; OrderedLocusNames=Os09g0347800, LOC_Os09g17850;
GN ORFNames=P0512H04.23, P0698G06.3;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Acetylates soluble but not nucleosomal H4.
CC {ECO:0000250|UniProtKB:O14929}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-
CC lysyl-[protein]; Xref=Rhea:RHEA:45948, Rhea:RHEA-COMP:9752,
CC Rhea:RHEA-COMP:10731, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:61930; EC=2.3.1.48;
CC Evidence={ECO:0000250|UniProtKB:O14929};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the HAT1 family. {ECO:0000305}.
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DR EMBL; AP005313; BAD28482.1; -; Genomic_DNA.
DR EMBL; AP005400; BAD28560.1; -; Genomic_DNA.
DR EMBL; AP008215; BAF24860.1; -; Genomic_DNA.
DR EMBL; AP014965; BAT07622.1; -; Genomic_DNA.
DR EMBL; AK101995; BAG95329.1; -; mRNA.
DR RefSeq; XP_015610693.1; XM_015755207.1.
DR AlphaFoldDB; Q6ES10; -.
DR SMR; Q6ES10; -.
DR STRING; 4530.OS09T0347800-01; -.
DR PaxDb; Q6ES10; -.
DR PRIDE; Q6ES10; -.
DR EnsemblPlants; Os09t0347800-01; Os09t0347800-01; Os09g0347800.
DR GeneID; 4346812; -.
DR Gramene; Os09t0347800-01; Os09t0347800-01; Os09g0347800.
DR KEGG; osa:4346812; -.
DR eggNOG; KOG2696; Eukaryota.
DR HOGENOM; CLU_046617_0_0_1; -.
DR InParanoid; Q6ES10; -.
DR OMA; YFINLDE; -.
DR OrthoDB; 708105at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR Genevisible; Q6ES10; OS.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:GOC.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0010485; F:H4 histone acetyltransferase activity; IBA:GO_Central.
DR GO; GO:0043967; P:histone H4 acetylation; IBA:GO_Central.
DR GO; GO:0031509; P:subtelomeric heterochromatin assembly; IEA:InterPro.
DR Gene3D; 3.90.360.10; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR019467; Hat1_N.
DR InterPro; IPR037113; Hat1_N_sf.
DR InterPro; IPR017380; Hist_AcTrfase_B-typ_cat-su.
DR PANTHER; PTHR12046; PTHR12046; 1.
DR Pfam; PF10394; Hat1_N; 1.
DR PIRSF; PIRSF038084; HAT-B_cat; 1.
DR SUPFAM; SSF55729; SSF55729; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase; Cytoplasm; Nucleus; Reference proteome; Transferase.
FT CHAIN 1..466
FT /note="Probable histone acetyltransferase type B catalytic
FT subunit"
FT /id="PRO_0000232127"
FT ACT_SITE 274
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000250|UniProtKB:O14929"
FT BINDING 240..242
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000250|UniProtKB:O14929"
FT BINDING 247..253
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000250|UniProtKB:O14929"
FT SITE 197
FT /note="Interaction with histone H4 N-terminus"
FT /evidence="ECO:0000250|UniProtKB:O14929"
SQ SEQUENCE 466 AA; 52113 MW; 84DC0FF3DAFACD98 CRC64;
MALKQKGTDA AADPKKRRRV GFSGIDAGVE ANECMKVFIA RNPDEAGSAN STSLQPFDLN
HFFGEDGKIY GYKNLKINVW ISAISFHAYA DISFEETSDG GKGITDLKPV LQNIFGENLV
EKDEFLKTFS KECEYLSNVV TDGNVIKHDA SIDEDSAVEI VRVELQGAAA FLYCRLVPLI
LLLVEGSTPI DITEHGWEML LVVKKSAQAS SSSNFLVLGF AAVHHFYHYP ESTRLRISQI
LVLPPYQGEG HGLRLLETIN SISESENIYD VTIEDPSDYL QYIRSSIDCL RLLTFDPIKP
ALCSMVSSLK DTNLSKRTSS LKMVPPSDLA ETVRQKLKIN KKQFLRCWEI LIYLNLDAED
RKSMDNFRAC IYDRIKGEIL GTSTGPNGKR LVQMPSNFDE ETCFAVYWTQ DGGDADDQTV
EQQPEDLKTQ EQQLNEVVDS QMEEIVEIAK NVTSRGKDKL SVSCSV
