ID   HAP28_DICDI             Reviewed;         208 AA.
AC   Q556U5; Q86JV9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=28 kDa heat- and acid-stable phosphoprotein homolog;
GN   ORFNames=DDB_G0273095;
GN   and
GN   ORFNames=DDB_G0273815;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the PDAP1 family. {ECO:0000305}.
CC   -!- CAUTION: The gene for this protein is duplicated in strains AX3 and
CC       AX4. These strains contain a duplication of a segment of 750 kb of
CC       chromosome 2 compared to the corresponding sequence in strain AX2.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000011; EAL70598.1; -; Genomic_DNA.
DR   EMBL; AAFI02000009; EAL70765.1; -; Genomic_DNA.
DR   RefSeq; XP_644524.1; XM_639432.1.
DR   RefSeq; XP_644726.1; XM_639634.1.
DR   AlphaFoldDB; Q556U5; -.
DR   SMR; Q556U5; -.
DR   STRING; 44689.DDB0168066; -.
DR   PaxDb; Q556U5; -.
DR   EnsemblProtists; EAL70598; EAL70598; DDB_G0273815.
DR   EnsemblProtists; EAL70765; EAL70765; DDB_G0273095.
DR   GeneID; 8618826; -.
DR   GeneID; 8619150; -.
DR   KEGG; ddi:DDB_G0273095; -.
DR   KEGG; ddi:DDB_G0273815; -.
DR   dictyBase; DDB_G0273095; -.
DR   dictyBase; DDB_G0273815; -.
DR   eggNOG; KOG3375; Eukaryota.
DR   HOGENOM; CLU_1323019_0_0_1; -.
DR   InParanoid; Q556U5; -.
DR   OMA; MGLWREP; -.
DR   Reactome; R-DDI-6798695; Neutrophil degranulation.
DR   PRO; PR:Q556U5; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   InterPro; IPR019380; Casein_kinase_sb_PP28.
DR   InterPro; IPR039876; HAP28.
DR   PANTHER; PTHR22055; PTHR22055; 1.
DR   Pfam; PF10252; PP28; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..208
FT                   /note="28 kDa heat- and acid-stable phosphoprotein homolog"
FT                   /id="PRO_0000347062"
FT   REGION          1..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          145..208
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          137..206
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        15..48
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..70
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..208
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   208 AA;  23634 MW;  D6D7F62A4811B5B8 CRC64;
     MAGGKRGGKV APTKTFGRDY ERSKGKISRD RVYDEEDIIK RNQESDSDDN SGSESGSENE
     TKNNNNKSKL GSDSSDDEPV IVSRNPNAKK PAAKRPPTTK KQQESDSEDD SDKESDSEDE
     IANPNRMKQV TKKLSEINVN AKVELSRREK EELARQAATQ RQNEKQQKSD LERLQVIRKQ
     REEAAKRKEE EKKANEEKMA ERRRLGLA