HAK8_ORYSJ
ID HAK8_ORYSJ Reviewed; 793 AA.
AC Q8VXB5; Q0DS26; Q10LS0;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Putative potassium transporter 8;
DE AltName: Full=OsHAK8;
GN Name=HAK8; OrderedLocusNames=Os03g0337500, LOC_Os03g21890;
GN ORFNames=OsJ_10761;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 93-793, AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=12376644; DOI=10.1104/pp.007781;
RA Banuelos M.A., Garciadeblas B., Cubero B., Rodriguez-Navarro A.;
RT "Inventory and functional characterization of the HAK potassium
RT transporters of rice.";
RL Plant Physiol. 130:784-795(2002).
RN [7]
RP GENE FAMILY.
RX PubMed=19302972; DOI=10.1016/s1673-8527(08)60103-4;
RA Yang Z., Gao Q., Sun C., Li W., Gu S., Xu C.;
RT "Molecular evolution and functional divergence of HAK potassium transporter
RT gene family in rice (Oryza sativa L.).";
RL J. Genet. Genomics 36:161-172(2009).
CC -!- FUNCTION: High-affinity potassium transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF11962.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC134885; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DP000009; ABF95828.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF11962.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000140; EAZ26845.1; -; Genomic_DNA.
DR EMBL; AJ427977; CAD20998.1; -; Genomic_DNA.
DR RefSeq; XP_015630461.1; XM_015774975.1.
DR RefSeq; XP_015630462.1; XM_015774976.1.
DR RefSeq; XP_015630463.1; XM_015774977.1.
DR RefSeq; XP_015630464.1; XM_015774978.1.
DR RefSeq; XP_015630465.1; XM_015774979.1.
DR AlphaFoldDB; Q8VXB5; -.
DR STRING; 4530.OS03T0337500-00; -.
DR PaxDb; Q8VXB5; -.
DR PRIDE; Q8VXB5; -.
DR GeneID; 9271735; -.
DR KEGG; osa:9271735; -.
DR eggNOG; ENOG502QPSA; Eukaryota.
DR InParanoid; Q8VXB5; -.
DR OrthoDB; 332035at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR InterPro; IPR003855; K+_transporter.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
DR TIGRFAMs; TIGR00794; kup; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Ion transport; Membrane; Potassium; Potassium transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..793
FT /note="Putative potassium transporter 8"
FT /id="PRO_0000209095"
FT TOPO_DOM 1..22
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 23..43
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..59
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 60..80
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 81..151
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..172
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 173..191
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 192..212
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 213..215
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 216..236
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 237..264
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..285
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 286..292
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 293..313
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 314..343
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 344..364
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 365..391
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 392..412
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 413..422
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 423..443
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 444..448
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 449..469
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 470..473
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 474..494
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 495..793
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 664..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..680
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 420
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 793 AA; 87653 MW; 2C5A1C69EAF180F7 CRC64;
MDLEFGRGMR SPQRDSWKTT LLLAYQSLGV VYGDLSISPL YVFKSTFAED IQHSETNEEI
FGVLSFVFWT LTLIPLIKYV SIVLRADDNG EGGTFALYSL ICRHANVSLL PNRQIADEEL
STYKLECSSE RTDKSCIKVW LEKHKKLHTA LLIMVLIGTC MVIGDGVLTP AISVFSAVSG
LEFSLSKDHR EYAVIPITCV ILAFLFALQH YGTHRVGFLF APIVLAWLIC MSALGLYNII
HWNPHVYQAL NPCYMFKFLK KTRKYGWMSL GGILLCMTGS EAMFADLGHF SYSAIQLAFT
SLVYPALILA YMGQAAYLSK HHDFYSNSQV GFYIAVPDKV RWPVLVLAIL ASVVGSQAII
SGTFSIINQS QSLSCFPRVK VVHTSDKIHG QIYIPEINWL LMILCIAVTV GFRDTKHMGN
ASGLAVITVM LVTTCLTSLV IMLCWRRPPV LALCFLLFFG SVEALYFSAS LIKFLEGAWL
PILLALFLMA VMLVWHYTTI KKYEFDLHNK VTLEWLLALG DKLGMVRVPG IGLVYTDLTS
GVPANFSRFV TNLPAFHQVL VFVCVKSVPV PYVFPAERYL IGRVGPPGHR SYRCIVRYGY
RDVHQDVDSF ETELVESLAT FIKLDASYRC SDASGGGGDH EPEEERGTRL AVIGSSHASY
DIQDSVQHSS AASVETTTTR RRSGGGDDDG SPGGGGGRAK QVRFFIDSHV ASPEAADNKQ
VAEELEALAA ARDAGTAFIL GHSHVQCKPG SSLLKRLAVD VGYNFLRRNC RGPDVALRVP
PASLLEVGMV YVL
