HAK7_ORYSJ
ID HAK7_ORYSJ Reviewed; 811 AA.
AC Q8H3P9; Q0D3S0; Q8VWK2;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 3.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Potassium transporter 7;
DE AltName: Full=OsHAK7;
GN Name=HAK7; OrderedLocusNames=Os07g0669700, LOC_Os07g47350;
GN ORFNames=P0625E02.129;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1), FUNCTION, TISSUE
RP SPECIFICITY, NOMENCLATURE, AND INDUCTION.
RC STRAIN=cv. Nipponbare;
RX PubMed=12376644; DOI=10.1104/pp.007781;
RA Banuelos M.A., Garciadeblas B., Cubero B., Rodriguez-Navarro A.;
RT "Inventory and functional characterization of the HAK potassium
RT transporters of rice.";
RL Plant Physiol. 130:784-795(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-529 (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY.
RX PubMed=19302972; DOI=10.1016/s1673-8527(08)60103-4;
RA Yang Z., Gao Q., Sun C., Li W., Gu S., Xu C.;
RT "Molecular evolution and functional divergence of HAK potassium transporter
RT gene family in rice (Oryza sativa L.).";
RL J. Genet. Genomics 36:161-172(2009).
CC -!- FUNCTION: High-affinity potassium transporter.
CC {ECO:0000269|PubMed:12376644}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8H3P9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8H3P9-2; Sequence=VSP_037671, VSP_037672;
CC -!- TISSUE SPECIFICITY: Expressed in roots and shoots.
CC {ECO:0000269|PubMed:12376644}.
CC -!- INDUCTION: By potassium starvation in both roots and shoots of young
CC seedlings. {ECO:0000269|PubMed:12376644}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC83599.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ427971; CAD20992.1; -; mRNA.
DR EMBL; AJ427976; CAD20997.1; -; Genomic_DNA.
DR EMBL; AP004570; BAC83599.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008213; BAF22503.2; -; Genomic_DNA.
DR EMBL; AP014963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK100652; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015646990.1; XM_015791504.1. [Q8H3P9-1]
DR RefSeq; XP_015646991.1; XM_015791505.1. [Q8H3P9-2]
DR AlphaFoldDB; Q8H3P9; -.
DR STRING; 4530.OS07T0669700-01; -.
DR PaxDb; Q8H3P9; -.
DR PRIDE; Q8H3P9; -.
DR GeneID; 4344235; -.
DR KEGG; osa:4344235; -.
DR eggNOG; ENOG502QPSA; Eukaryota.
DR InParanoid; Q8H3P9; -.
DR OrthoDB; 332035at2759; -.
DR BioCyc; MetaCyc:MON-14581; -.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR InterPro; IPR003855; K+_transporter.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
DR TIGRFAMs; TIGR00794; kup; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycoprotein; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..811
FT /note="Potassium transporter 7"
FT /id="PRO_0000209094"
FT TOPO_DOM 1..52
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 74..93
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 115..181
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 203..217
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 218..238
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 239..245
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 246..266
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 267..296
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..317
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 318..326
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 327..347
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 348..366
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 367..387
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 388..418
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 419..439
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 440..450
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 451..471
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 472..475
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 476..496
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 497..503
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 504..524
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 525..811
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 680..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 351
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 1..30
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_037671"
FT VAR_SEQ 31..40
FT /note="RVGVLMIVLL -> MDAETGPAAP (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_037672"
FT CONFLICT 122
FT /note="E -> G (in Ref. 5; AK100652)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 811 AA; 90850 MW; 43A2A5E499DC4AA6 CRC64;
MPSYQYLLSL LFYILDCTDR FSVIVTIHNH RVGVLMIVLL QDQWKSYCRT ISLLAFQSFG
VVYGDLSTSP LYVYKSAFSG RLNNYRDETT IFGLFSLIFW TLTLLPLLKY VIIVLNADDN
GEGGTFALYS LLCRHAKFSL LPNQQSADEE LSTYYQPGVG GIISSPLKRF LEKHRKLRTC
LLLFVLFGAC MVIGDGVFTP AISVLSAISG LKDPGPGGIP DGWVVFIACI VLVGLFALQH
RGTHRVAFMF APIVVVWLLS IGVIGLYNII HWNHRIFLAL SPHYVIKFFK MTGKDGWLSL
GGVLLAITGT EAMFADLGHF TAASIRLAFV GAIYPCLVLQ YMGQAAFLSR NMSAVEDSFY
QSVPRSLFWP VFVIATLAAV VGSQSIISAT FSIVKQCLSL GCFPRVKVVH TSRWIHGQIY
IPEINWILMV LCLAVTLGFR DTTVIGNAYG LACIVVMFVT TWLMALVIIF VWQKNILLAL
LFVVAFGSIE VVYLSAAVTK VPQGGWAPIV FAFVFMLVMY VWHYGSRRKY LFDLQNKVSM
KWILTLGPSL GIVRVPGIGL IYTELVTGVP SIFSHFVTNL PAFHQVLVFV CVKSVPVPFV
PEDERYLIGR IGPREYRMYR CIVRYGYKDV QKDDENFENH LVMSIAKFIQ MEAEEAASSG
SYESSEGRMA VIHTEDTTGT GLVMRDSNNE ASGTSLTRSS RSETLRSLQS IYEQESGSLS
RRRRVRFEIA EEERIDPQVR DELADLLDAK EAGVTYIIGH SYVKARKNSN FLKTFAIDYA
YSFLRKNCRG PAVALHIPHI SLVEVGMIYY V
