HAK6_ORYSJ
ID HAK6_ORYSJ Reviewed; 748 AA.
AC Q5JMH0; A0A0P0VCS4;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Potassium transporter 6;
DE AltName: Full=OsHAK6;
GN Name=HAK6; OrderedLocusNames=Os01g0932500, LOC_Os01g70660;
GN ORFNames=P0423A12.11, P0506E04.32;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY.
RX PubMed=19302972; DOI=10.1016/s1673-8527(08)60103-4;
RA Yang Z., Gao Q., Sun C., Li W., Gu S., Xu C.;
RT "Molecular evolution and functional divergence of HAK potassium transporter
RT gene family in rice (Oryza sativa L.).";
RL J. Genet. Genomics 36:161-172(2009).
CC -!- FUNCTION: High-affinity potassium transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
CC {ECO:0000305}.
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DR EMBL; AP003246; BAD87162.1; -; Genomic_DNA.
DR EMBL; AP003272; BAD87337.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF07212.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS76051.1; -; Genomic_DNA.
DR EMBL; AK107477; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015646586.1; XM_015791100.1.
DR AlphaFoldDB; Q5JMH0; -.
DR STRING; 4530.OS01T0932500-01; -.
DR PaxDb; Q5JMH0; -.
DR PRIDE; Q5JMH0; -.
DR EnsemblPlants; Os01t0932500-01; Os01t0932500-01; Os01g0932500.
DR GeneID; 4326820; -.
DR Gramene; Os01t0932500-01; Os01t0932500-01; Os01g0932500.
DR KEGG; osa:4326820; -.
DR eggNOG; ENOG502QPSA; Eukaryota.
DR HOGENOM; CLU_008142_4_0_1; -.
DR InParanoid; Q5JMH0; -.
DR OMA; VIWEVNG; -.
DR OrthoDB; 332035at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q5JMH0; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR InterPro; IPR003855; K+_transporter.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
DR TIGRFAMs; TIGR00794; kup; 1.
PE 2: Evidence at transcript level;
KW Ion transport; Membrane; Potassium; Potassium transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..748
FT /note="Potassium transporter 6"
FT /id="PRO_0000379532"
FT TOPO_DOM 1..68
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..91
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 92..113
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 114..134
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 135..199
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 200..220
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 221..243
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..264
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 265
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 266..286
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 287..319
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 320..340
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 341..348
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 349..369
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 370..381
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 382..402
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 403..438
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 439..459
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 460..470
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 471..491
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 492..497
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 498..518
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 519..523
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 524..544
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 545..748
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 30..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 124
FT /note="L -> P (in Ref. 5; AK107477)"
FT /evidence="ECO:0000305"
FT CONFLICT 224
FT /note="S -> P (in Ref. 5; AK107477)"
FT /evidence="ECO:0000305"
FT CONFLICT 649
FT /note="D -> G (in Ref. 5; AK107477)"
FT /evidence="ECO:0000305"
FT CONFLICT 660
FT /note="V -> D (in Ref. 5; AK107477)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 748 AA; 81886 MW; 875352013712D542 CRC64;
MVPPGNGNGA AAAAGNDVIL ELSTPGDDWS HELQGDDVEA NGGGNGDAPP RRTFSFGQAY
KTRHRQPQVF TVWQTLMLGY QSLGIVYGDL GTSPLYVFPS VVLPDADATD FLGILSLIIW
TLTLMSLVKY ALIVLKADDH GEGGTFALYS LLRQHVNFKG NIPVPLTRLE SDVHLKFHSK
RRSRPSRLQL FLENSPKAQL AITIIVLIGT CMLIGDGALT PAISVLSAVQ GIQSRSSHIK
QKHVVVLSAV ILVLLFLVQR FGTSRVSFTF SPIMLLWFAS IAGIGVYNIV MHYPPVLKAV
SPHYIYYYFA KNKRVGWEQL GAVILCITGA EAMFADMGHF NKSSIQVAFS TAVFPSLILA
YSGQAAYLIK NPGDLSTAFY SSVPAPLFWP MFVVSTLAAI VASQSLISAS YSIIRQSIAL
GCFPRTTVKH TSDKYEGQVY CPEINYVLMV VCVLITVGFQ GGPEIGRAFG VAVIWVMLLT
TTLMTVVMVV IWEVNGALAG GFFVFYLAIE GTYMTSLMTK VPQGGWVPFA ITVAFLSVTL
SWTYGRKKKR EYEARHAVGD GEFAGIVSRS ARVPGMCLFC TDLMDGVPPI VRHYAANTGS
LRELLLFVTF RTLPVRTVLA GERFLVAREG ARAGVYRCIA QYGYMDEQDM VGDDFVRAAV
AALVEVAAAA AEADSGEEEA EMIGRAPASG VSYVIGRTVL RMRRARNWPK RFVINELYRF
LQKNFRSNVS TLKLDHAKTL QVGMIYEI
