HAK4_ORYSJ
ID HAK4_ORYSJ Reviewed; 697 AA.
AC Q6YSA9; A0A0P0XGH8; Q0J551; Q9M7J7;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Probable potassium transporter 4;
DE AltName: Full=OsHAK4;
GN Name=HAK4; OrderedLocusNames=Os08g0466200, LOC_Os08g36340;
GN ORFNames=OsJ_27614, P0104B02.21;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 82-697.
RA Rubio F., Santa-Maria G.E., Rodriguez-Navarro A.;
RT "Cloning of Arabidopsis and barley cDNAs encoding HAK potassium
RT transporters in root and shoot cells.";
RL Physiol. Plantarum 109:34-43(2000).
RN [7]
RP NOMENCLATURE.
RX PubMed=12376644; DOI=10.1104/pp.007781;
RA Banuelos M.A., Garciadeblas B., Cubero B., Rodriguez-Navarro A.;
RT "Inventory and functional characterization of the HAK potassium
RT transporters of rice.";
RL Plant Physiol. 130:784-795(2002).
RN [8]
RP GENE FAMILY.
RX PubMed=19302972; DOI=10.1016/s1673-8527(08)60103-4;
RA Yang Z., Gao Q., Sun C., Li W., Gu S., Xu C.;
RT "Molecular evolution and functional divergence of HAK potassium transporter
RT gene family in rice (Oryza sativa L.).";
RL J. Genet. Genomics 36:161-172(2009).
CC -!- FUNCTION: High-affinity potassium transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP006461; BAD10774.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF23914.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT05800.1; -; Genomic_DNA.
DR EMBL; CM000145; EEE68836.1; -; Genomic_DNA.
DR EMBL; AK071698; BAG92635.1; -; mRNA.
DR EMBL; AF129485; AAF36497.1; -; mRNA.
DR RefSeq; XP_015649439.1; XM_015793953.1.
DR AlphaFoldDB; Q6YSA9; -.
DR STRING; 4530.OS08T0466200-01; -.
DR PaxDb; Q6YSA9; -.
DR PRIDE; Q6YSA9; -.
DR EnsemblPlants; Os08t0466200-01; Os08t0466200-01; Os08g0466200.
DR GeneID; 4345789; -.
DR Gramene; Os08t0466200-01; Os08t0466200-01; Os08g0466200.
DR KEGG; osa:4345789; -.
DR eggNOG; ENOG502QPSA; Eukaryota.
DR HOGENOM; CLU_008142_4_0_1; -.
DR InParanoid; Q6YSA9; -.
DR OMA; VKYICIA; -.
DR OrthoDB; 332035at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q6YSA9; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR InterPro; IPR003855; K+_transporter.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
DR TIGRFAMs; TIGR00794; kup; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Ion transport; Membrane; Potassium; Potassium transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..697
FT /note="Probable potassium transporter 4"
FT /id="PRO_0000209093"
FT TOPO_DOM 1..29
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 30..50
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 51..66
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 88..152
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 153..173
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 174..189
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 211..217
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 218..238
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 239..271
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 293..300
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 301..321
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 322..338
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 339..359
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 360..390
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 391..411
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 412..422
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 423..443
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 444..447
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 448..468
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 469..475
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 476..496
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 497..697
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 55
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 264
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 389
FT /note="G -> R (in Ref. 6; AAF36497)"
FT /evidence="ECO:0000305"
FT CONFLICT 396
FT /note="T -> N (in Ref. 6; AAF36497)"
FT /evidence="ECO:0000305"
FT CONFLICT 410..414
FT /note="GFGDG -> RFRER (in Ref. 6; AAF36497)"
FT /evidence="ECO:0000305"
FT CONFLICT 612
FT /note="A -> S (in Ref. 6; AAF36497)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 697 AA; 76826 MW; E542AA7CFF74FEB5 CRC64;
MSSSHTVTVS MDVEAGQKNK DKKGISQDLI LAYKTLGVVF GGLVTSPLYV YPSMNLTNPT
EEDYLGIYSI MFWTLTLIGV VKYICIALNA DDHGEGGTFA MYSLLCQHAN IGILPSKKIY
TEEENLISNQ PVVAGRPGRL RRFIESSIIA RRLLLLTAIL GMCMLIGDGI LTPAISVLSA
IDGLRGPFPS VSKPAVEGLS AAILVGLFLL QKYGTSKVSF MFSPIMAAWT FATPVIGVYS
IWRYYPGIFK AMSPHYIVRF FMTNQTRGWQ LLGGTVLCIT GAEAMFADLG HFSKRSIQIA
FMSSIYPSLV LTYAGQTAYL INNVDDFSDG FYKFVPRPVY WPMFIIATLA AIVASQSLIS
ATFSVIKQSV VLDYFPRVKV VHTSKDKEGE VYSPETNYML MLLCVGVILG FGDGKDIGNA
FGVVVILVML ITTILLTLVM LIIWGTHVVL VALYLVPFLL LEATYVSAVC TKILRGGWVP
FAVSVALAAV MFGWYYGRQR KTEYEAANKV TLERLGELLS GPGLRRVPGL CFFYSNRQDG
GWLTPVLAHY IRNMRSLHEV TVFLTLRYLL VAKVDGKDRV QAVRRLGPAG VYGCTIQYGY
ADAIDFEEDD IAGQVVGALR ERVVDGEEEG ERVEAARAAG VVHVRGKMRF HVGKDTRLFD
RVLLGFYELL HGACRSALPA LGIPLQQRVE IGMLYKA
