ID   H3_VOLCA                Reviewed;         135 AA.
AC   P08437;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Histone H3;
GN   Name=H3-I;
GN   and
GN   Name=H3-II;
OS   Volvox carteri (Green alga).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Volvocaceae; Volvox.
OX   NCBI_TaxID=3067;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=f. Nagariensis / HK10;
RX   PubMed=2836811; DOI=10.1093/nar/16.9.4121;
RA   Mueller K., Schmitt R.;
RT   "Histone genes of Volvox carteri: DNA sequence and organization of two H3-
RT   H4 gene loci.";
RL   Nucleic Acids Res. 16:4121-4136(1988).
CC   -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact
CC       DNA into chromatin, limiting DNA accessibility to the cellular
CC       machineries which require DNA as a template. Histones thereby play a
CC       central role in transcription regulation, DNA repair, DNA replication
CC       and chromosomal stability. DNA accessibility is regulated via a complex
CC       set of post-translational modifications of histones, also called
CC       histone code, and nucleosome remodeling.
CC   -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC       each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC       two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC       DNA.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the histone H3 family. {ECO:0000305}.
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DR   EMBL; X06963; CAA30035.1; -; Genomic_DNA.
DR   EMBL; X06964; CAA30037.1; -; Genomic_DNA.
DR   PIR; S00940; S00940.
DR   RefSeq; XP_002946112.1; XM_002946066.1.
DR   RefSeq; XP_002946114.1; XM_002946068.1.
DR   RefSeq; XP_002947277.1; XM_002947231.1.
DR   RefSeq; XP_002947411.1; XM_002947365.1.
DR   RefSeq; XP_002947524.1; XM_002947478.1.
DR   RefSeq; XP_002947836.1; XM_002947790.1.
DR   RefSeq; XP_002953084.1; XM_002953038.1.
DR   RefSeq; XP_002953085.1; XM_002953039.1.
DR   RefSeq; XP_002956797.1; XM_002956751.1.
DR   RefSeq; XP_002956851.1; XM_002956805.1.
DR   AlphaFoldDB; P08437; -.
DR   SMR; P08437; -.
DR   GeneID; 9620098; -.
DR   GeneID; 9620487; -.
DR   GeneID; 9620512; -.
DR   GeneID; 9621100; -.
DR   GeneID; 9621365; -.
DR   GeneID; 9621883; -.
DR   GeneID; 9622573; -.
DR   GeneID; 9622617; -.
DR   GeneID; 9627802; -.
DR   GeneID; 9627803; -.
DR   KEGG; vcn:VOLCADRAFT_101585; -.
DR   KEGG; vcn:VOLCADRAFT_108835; -.
DR   KEGG; vcn:VOLCADRAFT_56755; -.
DR   KEGG; vcn:VOLCADRAFT_56978; -.
DR   KEGG; vcn:VOLCADRAFT_57055; -.
DR   KEGG; vcn:VOLCADRAFT_57650; -.
DR   KEGG; vcn:VOLCADRAFT_63067; -.
DR   KEGG; vcn:VOLCADRAFT_63197; -.
DR   KEGG; vcn:VOLCADRAFT_97851; -.
DR   KEGG; vcn:VOLCADRAFT_97860; -.
DR   OMA; HIVMART; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR007125; Histone_H2A/H2B/H3.
DR   InterPro; IPR000164; Histone_H3/CENP-A.
DR   PANTHER; PTHR11426; PTHR11426; 1.
DR   Pfam; PF00125; Histone; 1.
DR   PRINTS; PR00622; HISTONEH3.
DR   SMART; SM00428; H3; 1.
DR   SUPFAM; SSF47113; SSF47113; 1.
DR   PROSITE; PS00322; HISTONE_H3_1; 1.
DR   PROSITE; PS00959; HISTONE_H3_2; 1.
PE   3: Inferred from homology;
KW   Chromosome; DNA-binding; Nucleosome core; Nucleus.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000305"
FT   CHAIN           2..135
FT                   /note="Histone H3"
FT                   /id="PRO_0000221352"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   135 AA;  15310 MW;  1748F7FEC8E680EC CRC64;
     MARTKQTARK STGGKAPRKQ LATKAARKTP ATGGVKKPHR YRPGTVALRE IRKYQKSTEL
     LIRKLPFQRL VREIAQDFKT DLRFQSQAVL ALQEAAEAYL VGLFEDTNLC AIHAKRVTIM
     PKDIQLARRI RGERA