ID   GSM1_VANPO              Reviewed;         476 AA.
AC   A7TQK0;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Glucose starvation modulator protein 1;
GN   Name=GSM1; ORFNames=Kpol_463p14;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; DS480459; EDO15464.1; -; Genomic_DNA.
DR   RefSeq; XP_001643322.1; XM_001643272.1.
DR   AlphaFoldDB; A7TQK0; -.
DR   STRING; 436907.A7TQK0; -.
DR   EnsemblFungi; EDO15464; EDO15464; Kpol_463p14.
DR   GeneID; 5543531; -.
DR   KEGG; vpo:Kpol_463p14; -.
DR   eggNOG; ENOG502R2ZP; Eukaryota.
DR   HOGENOM; CLU_010748_2_2_1; -.
DR   InParanoid; A7TQK0; -.
DR   OMA; CHEKHLQ; -.
DR   OrthoDB; 681770at2759; -.
DR   PhylomeDB; A7TQK0; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..476
FT                   /note="Glucose starvation modulator protein 1"
FT                   /id="PRO_0000406491"
FT   DOMAIN          347..417
FT                   /note="PAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DNA_BIND        20..48
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          48..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   476 AA;  54343 MW;  63B8466A230EA46B CRC64;
     MTKKLPVEKK LSRKPISRAC EFCHLKHLQC DTGRPCQNCV KRNIGKGCKD KERKTKKRQL
     KNNTSNSDLE NIPKQVKTDI IPGPIRMTPT TAIYQQNNDF SIKKIHSLTT ILNSTNSFLG
     TDFVNTGNID DPKNEINNPP STLSISTNGS NPDSTFDSIW AGDEYKKLND IIGLGRASGL
     SLSHPNTETE KGIVHVNSIS KINSRPFISL SIDSTGGSID EYNLRYSIPS DSTKFKQLKI
     DTNESFLSPY MFRKAIKTPK EFHEKRSTIL PHNYRIGYRY LLKTLHNMFI NETTLDAETL
     SIRKQQVSYI VKSILVKYTE NFISISSNMV EEDLLLQELT LQRTLLEFES MSRLVPATPI
     AIWRRTGEIC YISSEFTSLT GFTKKEVLNK RSYIFEYMDH ESVIHYFETI YNKLSFNISS
     NAAKFSSSNN FLFTKCNLLL NNGSFLKCVC CWTVTRDTLK IPVLFTGHFM PIFDVQ