ID   GPT1_CANAX              Reviewed;         553 AA.
AC   O74248;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Putative polyamine transporter;
GN   Name=GPT1;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11284011; DOI=10.1002/yea.697;
RA   McNemar M.D., Gorman J.A., Buckley H.R.;
RT   "Isolation of a gene encoding a putative polyamine transporter from Candida
RT   albicans, GPT1.";
RL   Yeast 18:555-561(2001).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. {ECO:0000305}.
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DR   EMBL; AF080132; AAC31569.1; -; Genomic_DNA.
DR   AlphaFoldDB; O74248; -.
DR   SMR; O74248; -.
DR   VEuPathDB; FungiDB:C1_05080W_A; -.
DR   VEuPathDB; FungiDB:CAWG_00890; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   Pfam; PF13520; AA_permease_2; 1.
PE   3: Inferred from homology;
KW   Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..553
FT                   /note="Putative polyamine transporter"
FT                   /id="PRO_0000054153"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        280..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        333..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        397..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        453..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        485..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   553 AA;  60634 MW;  197DACB76C5FBC9E CRC64;
     MGIASILSNK NITINVDHVI DSDEAMLLAI GYRQELRREF SLWSIFAVSF SVLGLLPSIA
     ACFDYQQLVV GMSPLPWLIA MIFITSVAYS MAEIASAFPC SAGTPYAVSQ LAPKKYASFL
     TWFTCWTNWS CQITAAPSVS YSCACMMLAL HSFTDPSFVA SNAQIFGLTT GIQVLCAFMA
     CFPTKWVARF SSAGTTCNIV FLVVVFIMIL GGNKRDQIKE GISKFNSNST AWGLDNQAEW
     PTGLSFLISF MGVIWAMSGY DSPFHLAEKC SNAAVAAPRA IVLTSTVGGL IGFMFMIAIA
     YTLVDLNQIS ADPESLGQPF VTYLTQIMDK NLVIGATALT IISSFFMAQN CLLASSRVTY
     AYARDGLFPL SGIWKKVSPK TQTPINAVIM NFIVEELLLL LIFGGDVSIG SIFSIGALAG
     FISFTMPTLL KITYARKTFQ PGPWNLGKWS EPIGWVSVAF VGLMVPILCF PTVKGADLTP
     TEMNWTCLVY FGLILLTTIW FVVYARRWYV GPRTNISEED IVYGEKTEDE GDEIPDVIDG
     QKVSISSTEK RYQ