ID   GNGF_STRPQ              Reviewed;         325 AA.
AC   P0DG79; Q878G8; Q8K850;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Putative gluconeogenesis factor {ECO:0000255|HAMAP-Rule:MF_00973};
GN   OrderedLocusNames=SPs1392;
OS   Streptococcus pyogenes serotype M3 (strain SSI-1).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=193567;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SSI-1;
RX   PubMed=12799345; DOI=10.1101/gr.1096703;
RA   Nakagawa I., Kurokawa K., Yamashita A., Nakata M., Tomiyasu Y.,
RA   Okahashi N., Kawabata S., Yamazaki K., Shiba T., Yasunaga T., Hayashi H.,
RA   Hattori M., Hamada S.;
RT   "Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-
RT   scale genomic rearrangement in invasive strains and new insights into phage
RT   evolution.";
RL   Genome Res. 13:1042-1055(2003).
CC   -!- FUNCTION: Required for morphogenesis under gluconeogenic growth
CC       conditions. {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SIMILARITY: Belongs to the gluconeogenesis factor family.
CC       {ECO:0000255|HAMAP-Rule:MF_00973}.
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DR   EMBL; BA000034; BAC64487.1; -; Genomic_DNA.
DR   RefSeq; WP_011017561.1; NC_004606.1.
DR   AlphaFoldDB; P0DG79; -.
DR   SMR; P0DG79; -.
DR   KEGG; sps:SPs1392; -.
DR   HOGENOM; CLU_044041_0_1_9; -.
DR   OMA; LCGDDDW; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043743; F:LPPG:FO 2-phospho-L-lactate transferase activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10680; -; 1.
DR   HAMAP; MF_00973; Gluconeogen_factor; 1.
DR   InterPro; IPR002882; CofD.
DR   InterPro; IPR038136; CofD-like_dom_sf.
DR   InterPro; IPR010119; Gluconeogen_factor.
DR   PANTHER; PTHR30135; PTHR30135; 1.
DR   Pfam; PF01933; CofD; 1.
DR   SUPFAM; SSF142338; SSF142338; 1.
DR   TIGRFAMs; TIGR01826; CofD_related; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..325
FT                   /note="Putative gluconeogenesis factor"
FT                   /id="PRO_0000411629"
SQ   SEQUENCE   325 AA;  35737 MW;  E751456F26202851 CRC64;
     MKNPKMTVIG GGTGISIILK SLRNEAVDIT AVVTVADDGG SSGELRNAMQ LAPPGDLRNV
     LLAMSDMPKF YERVFQYRFN ESDGALAGHP LGNLIIAGIS EMQGSTYNAI QILTKFFHIT
     GKIYPSSEQA LTLHAVFKDG HEVAGESSIA KYQGMIDHVY VTNTYNDQKP QASRKVVEAI
     LESDMIVLGP GSLFTSILPN LVIPEIKEAL RQTKAEVVYI CNIMTQYGET EQFSDADHVA
     VLNQHLGRDL IDTVLVNVAK VPQAYMNSNK FDEYLVQVDH DFAGLCRAAK RVISSYFLRL
     ENGGAFHDGN LVVEELMNLV RIVKQ