ID   GNGF_MYCTO              Reviewed;         342 AA.
AC   P9WMU4; L0T6L6; P71691;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Putative gluconeogenesis factor {ECO:0000255|HAMAP-Rule:MF_00973};
GN   OrderedLocusNames=MT1465;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Required for morphogenesis under gluconeogenic growth
CC       conditions. {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- PTM: Phosphorylated by PknA and/or PknB. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the gluconeogenesis factor family.
CC       {ECO:0000255|HAMAP-Rule:MF_00973}.
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DR   EMBL; AE000516; AAK45730.1; -; Genomic_DNA.
DR   PIR; C70903; C70903.
DR   RefSeq; WP_003407352.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WMU4; -.
DR   SMR; P9WMU4; -.
DR   EnsemblBacteria; AAK45730; AAK45730; MT1465.
DR   GeneID; 45425400; -.
DR   KEGG; mtc:MT1465; -.
DR   PATRIC; fig|83331.31.peg.1574; -.
DR   HOGENOM; CLU_044041_1_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043743; F:LPPG:FO 2-phospho-L-lactate transferase activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10680; -; 1.
DR   HAMAP; MF_00973; Gluconeogen_factor; 1.
DR   InterPro; IPR002882; CofD.
DR   InterPro; IPR038136; CofD-like_dom_sf.
DR   InterPro; IPR010119; Gluconeogen_factor.
DR   PANTHER; PTHR30135; PTHR30135; 1.
DR   Pfam; PF01933; CofD; 1.
DR   SUPFAM; SSF142338; SSF142338; 1.
DR   TIGRFAMs; TIGR01826; CofD_related; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Phosphoprotein.
FT   CHAIN           1..342
FT                   /note="Putative gluconeogenesis factor"
FT                   /id="PRO_0000427241"
FT   REGION          318..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         325
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   342 AA;  35823 MW;  D38C002F8C0BA16D CRC64;
     MTDGIVALGG GHGLYATLSA ARRLTPYVTA VVTVADDGGS SGRLRSELDV VPPGDLRMAL
     AALASDSPHG RLWATILQHR FGGSGALAGH PIGNLMLAGL SEVLADPVAA LDELGRILGV
     KGRVLPMCPV ALQIEADVSG LEADPRMFRL IRGQVAIATT PGKVRRVRLL PTDPPATRQA
     VDAIMAADLV VLGPGSWFTS VIPHVLVPGL AAALRATSAR RALVLNLVAE PGETAGFSVE
     RHLHVLAQHA PGFTVHDIII DAERVPSERE REQLRRTATM LQAEVHFADV ARPGTPLHDP
     GKLAAVLDGV CARDVGASEP PVAATQEIPI DGGRPRGDDA WR