ID   GNGF_MYCLE              Reviewed;         359 AA.
AC   Q9CCN9;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Putative gluconeogenesis factor {ECO:0000255|HAMAP-Rule:MF_00973};
GN   OrderedLocusNames=ML0564;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- FUNCTION: Required for morphogenesis under gluconeogenic growth
CC       conditions. {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SIMILARITY: Belongs to the gluconeogenesis factor family.
CC       {ECO:0000255|HAMAP-Rule:MF_00973}.
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DR   EMBL; AL583918; CAC30072.1; -; Genomic_DNA.
DR   PIR; D86979; D86979.
DR   RefSeq; NP_301478.1; NC_002677.1.
DR   RefSeq; WP_010907802.1; NC_002677.1.
DR   AlphaFoldDB; Q9CCN9; -.
DR   SMR; Q9CCN9; -.
DR   STRING; 272631.ML0564; -.
DR   EnsemblBacteria; CAC30072; CAC30072; CAC30072.
DR   KEGG; mle:ML0564; -.
DR   PATRIC; fig|272631.5.peg.975; -.
DR   Leproma; ML0564; -.
DR   eggNOG; COG0391; Bacteria.
DR   HOGENOM; CLU_044041_1_0_11; -.
DR   OMA; LCGDDDW; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043743; F:LPPG:FO 2-phospho-L-lactate transferase activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10680; -; 1.
DR   HAMAP; MF_00973; Gluconeogen_factor; 1.
DR   InterPro; IPR002882; CofD.
DR   InterPro; IPR038136; CofD-like_dom_sf.
DR   InterPro; IPR010119; Gluconeogen_factor.
DR   PANTHER; PTHR30135; PTHR30135; 1.
DR   Pfam; PF01933; CofD; 1.
DR   SUPFAM; SSF142338; SSF142338; 1.
DR   TIGRFAMs; TIGR01826; CofD_related; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..359
FT                   /note="Putative gluconeogenesis factor"
FT                   /id="PRO_0000107810"
FT   REGION          317..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   359 AA;  37442 MW;  D19DBA2A604B6157 CRC64;
     MISPGSPPSI VALGGGHGLY VTLSAARRLT PYVTAIVTVA DDGGSSGRLR SELGVVPPGD
     LRMALAALAS DSPYGRLWAT ILQHRFGGSG ALAGHPIGNL MLAGLSEVLA DPVAALDEVG
     RILGVKGRVL PMCPIALQIE ADVSGLEADP RIFRLIRGQV AIASTPGKVR RVRLLPVDPP
     ATRQAVDAIM AANLVVLGPG SWFTSVIPHV LVPGLVTALR ATTARRALVL NLAAGPGETA
     GFSVERHLHV LAQHAPGFTV HDIIIDADRV PNNREREQLR RAATLLQAEV HFVDVARPGT
     SLHDPGKLAT ALDGVRVGNQ DSSAPTVAAT EQIRLDGKRP QTGVNGPVGK GPRGDDAWR