ID   GNGF_ECO57              Reviewed;         302 AA.
AC   P58585;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Putative gluconeogenesis factor {ECO:0000255|HAMAP-Rule:MF_00973};
GN   Name=ybhK; OrderedLocusNames=Z0999, ECs0858;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Required for morphogenesis under gluconeogenic growth
CC       conditions. {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SIMILARITY: Belongs to the gluconeogenesis factor family.
CC       {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005174; AAG55151.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34281.1; -; Genomic_DNA.
DR   PIR; B90736; B90736.
DR   PIR; C85586; C85586.
DR   RefSeq; NP_308885.1; NC_002695.1.
DR   RefSeq; WP_001301716.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P58585; -.
DR   SMR; P58585; -.
DR   STRING; 155864.EDL933_0901; -.
DR   EnsemblBacteria; AAG55151; AAG55151; Z0999.
DR   EnsemblBacteria; BAB34281; BAB34281; ECs_0858.
DR   GeneID; 917602; -.
DR   KEGG; ece:Z0999; -.
DR   KEGG; ecs:ECs_0858; -.
DR   PATRIC; fig|386585.9.peg.972; -.
DR   eggNOG; COG0391; Bacteria.
DR   HOGENOM; CLU_044041_2_0_6; -.
DR   OMA; LCGDDDW; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043743; F:LPPG:FO 2-phospho-L-lactate transferase activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10680; -; 1.
DR   HAMAP; MF_00973; Gluconeogen_factor; 1.
DR   InterPro; IPR002882; CofD.
DR   InterPro; IPR038136; CofD-like_dom_sf.
DR   InterPro; IPR010119; Gluconeogen_factor.
DR   PANTHER; PTHR30135; PTHR30135; 1.
DR   Pfam; PF01933; CofD; 1.
DR   SUPFAM; SSF142338; SSF142338; 1.
DR   TIGRFAMs; TIGR01826; CofD_related; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..302
FT                   /note="Putative gluconeogenesis factor"
FT                   /id="PRO_0000107798"
SQ   SEQUENCE   302 AA;  32731 MW;  4138C3ED2C4DC2C4 CRC64;
     MRNRTLADLD RVVALGGGHG LGRVLSSLSS LGSRLTGIVT TTDNGGSTGR IRRSEGGIAW
     GDMRNCLNQL ITEPSVASAM FEYRFGGNGE LSGHNLGNLM LKALDHLSVR PLEAINLIRN
     LLKVDAHLIP MSEHPVDLMA IDDQGHEVYG EVNIDQLTTP IQELLLTPNV PATREAVHAI
     NEADLIIIGP GSFYTSLMPI LLLKEIAQAL RRTPAPMVYI GNLGRELSLP AANLKLESKL
     AIMEQYVGKK VIDAVIVGPK VDVSAVKERI VIQEVLEASD IPYRHDRQLL HSALEKALQA
     LG