ID   GNGF_AQUAE              Reviewed;         328 AA.
AC   O66974;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Putative gluconeogenesis factor {ECO:0000255|HAMAP-Rule:MF_00973};
GN   OrderedLocusNames=aq_778;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Required for morphogenesis under gluconeogenic growth
CC       conditions. {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00973}.
CC   -!- SIMILARITY: Belongs to the gluconeogenesis factor family.
CC       {ECO:0000255|HAMAP-Rule:MF_00973}.
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DR   EMBL; AE000657; AAC06942.1; -; Genomic_DNA.
DR   PIR; C70368; C70368.
DR   RefSeq; NP_213535.1; NC_000918.1.
DR   RefSeq; WP_010880473.1; NC_000918.1.
DR   AlphaFoldDB; O66974; -.
DR   SMR; O66974; -.
DR   STRING; 224324.aq_778; -.
DR   EnsemblBacteria; AAC06942; AAC06942; aq_778.
DR   KEGG; aae:aq_778; -.
DR   PATRIC; fig|224324.8.peg.619; -.
DR   eggNOG; COG0391; Bacteria.
DR   HOGENOM; CLU_044041_0_1_0; -.
DR   InParanoid; O66974; -.
DR   OMA; LCGDDDW; -.
DR   OrthoDB; 665169at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043743; F:LPPG:FO 2-phospho-L-lactate transferase activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10680; -; 1.
DR   HAMAP; MF_00973; Gluconeogen_factor; 1.
DR   InterPro; IPR002882; CofD.
DR   InterPro; IPR038136; CofD-like_dom_sf.
DR   InterPro; IPR010119; Gluconeogen_factor.
DR   PANTHER; PTHR30135; PTHR30135; 1.
DR   Pfam; PF01933; CofD; 1.
DR   SUPFAM; SSF142338; SSF142338; 1.
DR   TIGRFAMs; TIGR01826; CofD_related; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..328
FT                   /note="Putative gluconeogenesis factor"
FT                   /id="PRO_0000107802"
SQ   SEQUENCE   328 AA;  35957 MW;  30BB214E99958F6B CRC64;
     MKKVNVVAIG GGTGLSSLLR GLKIEVGRSI GRLSAIVTVA DSGGSTGRLR KIYNIPAPGD
     IRNCIVALSD AEELMQKLFQ YRFKGDGLEG HAFGNLFLTA LTDITGSFLK AIKETSKILK
     TKGDIIPSTY ENVNLVAEFD DGKVIKGEEE ITEYGKKGHK VVNIWLEPKN PKAPEEAIER
     IKEADLIIIG PGSLFTSILP NFLVPQIREA VKESRALKVF VVNVMTQPGE TDNFTAWDHI
     DTFLKFSGID LVDVAVVNTQ MPSNGLLKKY LEQNQEPVTP DVGRIGREGI TVYAENLIGE
     SGDFVRHDPQ KLTEVILKIL ENELLSKV