GLPT1_ARATH
ID GLPT1_ARATH Reviewed; 523 AA.
AC Q9C5L3; A0A1I9LTK8; Q9STY1;
DT 11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Putative glycerol-3-phosphate transporter 1;
DE Short=G-3-P transporter 1;
DE AltName: Full=Glycerol-3-phosphate permease 1;
DE Short=AtG3Pp1;
DE Short=G-3-P permease 1;
DE AltName: Full=Protein PHOSPHATE STARVATION-INDUCED GENE 3;
DE Short=AtPS3;
GN OrderedLocusNames=At3g47420; ORFNames=T21L8.170;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP INDUCTION.
RX PubMed=15894620; DOI=10.1073/pnas.0500778102;
RA Miura K., Rus A., Sharkhuu A., Yokoi S., Karthikeyan A.S., Raghothama K.G.,
RA Baek D., Koo Y.D., Jin J.B., Bressan R.A., Yun D.-J., Hasegawa P.M.;
RT "The Arabidopsis SUMO E3 ligase SIZ1 controls phosphate deficiency
RT responses.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:7760-7765(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- INDUCTION: By inorganic phosphate (Pi) starvation.
CC {ECO:0000269|PubMed:15894620}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB51214.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AL096860; CAB51214.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE78279.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65916.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65917.1; -; Genomic_DNA.
DR EMBL; AF325105; AAK17173.1; -; mRNA.
DR EMBL; AF360170; AAK25880.1; -; mRNA.
DR PIR; T12997; T12997.
DR RefSeq; NP_001327852.1; NM_001339309.1.
DR RefSeq; NP_001327853.1; NM_001339308.1.
DR RefSeq; NP_566891.1; NM_114610.4.
DR AlphaFoldDB; Q9C5L3; -.
DR SMR; Q9C5L3; -.
DR STRING; 3702.AT3G47420.1; -.
DR iPTMnet; Q9C5L3; -.
DR PaxDb; Q9C5L3; -.
DR PRIDE; Q9C5L3; -.
DR ProteomicsDB; 247397; -.
DR EnsemblPlants; AT3G47420.1; AT3G47420.1; AT3G47420.
DR EnsemblPlants; AT3G47420.2; AT3G47420.2; AT3G47420.
DR EnsemblPlants; AT3G47420.3; AT3G47420.3; AT3G47420.
DR GeneID; 823896; -.
DR Gramene; AT3G47420.1; AT3G47420.1; AT3G47420.
DR Gramene; AT3G47420.2; AT3G47420.2; AT3G47420.
DR Gramene; AT3G47420.3; AT3G47420.3; AT3G47420.
DR KEGG; ath:AT3G47420; -.
DR Araport; AT3G47420; -.
DR TAIR; locus:2099585; AT3G47420.
DR eggNOG; KOG2533; Eukaryota.
DR HOGENOM; CLU_001265_31_6_1; -.
DR InParanoid; Q9C5L3; -.
DR OMA; GTLMWGY; -.
DR OrthoDB; 964162at2759; -.
DR PhylomeDB; Q9C5L3; -.
DR BRENDA; 7.6.2.10; 399.
DR PRO; PR:Q9C5L3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9C5L3; baseline and differential.
DR Genevisible; Q9C5L3; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0055062; P:phosphate ion homeostasis; IEP:TAIR.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR000849; Sugar_P_transporter.
DR Pfam; PF07690; MFS_1; 1.
DR PIRSF; PIRSF002808; Hexose_phosphate_transp; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Sugar transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..523
FT /note="Putative glycerol-3-phosphate transporter 1"
FT /id="PRO_0000403112"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 468..488
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 523 AA; 56309 MW; BB7A40E86F37C455 CRC64;
MGSLMQSEPE MEKKPIGIRF LERIKGSKLS YSAYQAIVLI VTFLAYASYH AARKTTSIVK
SALDPQSPDT GLNSLLLRFT SFGSSVKEEG GWAPFNGPDG TVLLGEIDVA FLAVYAFGMY
FAGHLGDRMN LRIFLTVGMI GTGLFTSLFG VGYWGNIHSF YYFLIMQMLA GLFQSSGWPS
VVAVVGNWFN KKKRGLIMGI WNAHTSVGNI TGSLIAAAML RYGWGWSFVV PGVIIVVIGL
VNYAFLPVSP ENVGAERDEV LDSSSEKIGN SVNEPLLLSS SDSETDDKKR AVGFIEAWRI
PGVAPFALCL FFAKLVAYTF LYWLPFYVSH TAIEGEYLSD ETAGNLSTMF DVGGVVGGIM
AGYISDRIGA RAITAASFMY CSIPALFFYR SYGHVSLLAN ASLMFLTGML VNGPYALITT
AVSADLGTHS SLKGNSRALA TVTAIIDGTG SVGAAVGPLL TGYISSRGSW TAVFTMLMGA
AFVAGLLLTR LVMAEVAEKI AESRPSEECR SPVDYVQDHV MEV
