GLIP5_ARATH
ID GLIP5_ARATH Reviewed; 385 AA.
AC Q9SSA7;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=GDSL esterase/lipase 5;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase 5;
DE Flags: Precursor;
GN Name=GLIP5; OrderedLocusNames=At1g53920; ORFNames=T18A20.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=16126835; DOI=10.1105/tpc.105.034819;
RA Oh I.S., Park A.R., Bae M.S., Kwon S.J., Kim Y.S., Lee J.E., Kang N.Y.,
RA Lee S., Cheong H., Park O.K.;
RT "Secretome analysis reveals an Arabidopsis lipase involved in defense
RT against Alternaria brassicicola.";
RL Plant Cell 17:2832-2847(2005).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF02864.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC009324; AAF02864.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33025.1; -; Genomic_DNA.
DR PIR; E96579; E96579.
DR RefSeq; NP_175795.2; NM_104270.3.
DR AlphaFoldDB; Q9SSA7; -.
DR SMR; Q9SSA7; -.
DR STRING; 3702.AT1G53920.1; -.
DR PaxDb; Q9SSA7; -.
DR PRIDE; Q9SSA7; -.
DR ProteomicsDB; 248621; -.
DR EnsemblPlants; AT1G53920.1; AT1G53920.1; AT1G53920.
DR GeneID; 841830; -.
DR Gramene; AT1G53920.1; AT1G53920.1; AT1G53920.
DR KEGG; ath:AT1G53920; -.
DR Araport; AT1G53920; -.
DR TAIR; locus:2197014; AT1G53920.
DR eggNOG; ENOG502QQWV; Eukaryota.
DR HOGENOM; CLU_015101_0_2_1; -.
DR InParanoid; Q9SSA7; -.
DR OMA; DYMSPFL; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9SSA7; -.
DR BioCyc; ARA:AT1G53920-MON; -.
DR PRO; PR:Q9SSA7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SSA7; baseline and differential.
DR Genevisible; Q9SSA7; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; ISS:TAIR.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR044552; GLIP1-5/GLL25.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR PANTHER; PTHR45966; PTHR45966; 1.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..35
FT /evidence="ECO:0000255"
FT CHAIN 36..385
FT /note="GDSL esterase/lipase 5"
FT /id="PRO_0000367338"
FT ACT_SITE 55
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 345
FT /evidence="ECO:0000250"
FT ACT_SITE 348
FT /evidence="ECO:0000250"
FT CARBOHYD 45
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 66
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 194
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 211
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 289
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 385 AA; 43458 MW; 0AE87C8A39621794 CRC64;
MRESTLMEKV TRRTISSFIF FIVSSTILFL AGKSSAKISH NGDNNVTALF LFGDSFLDAG
NNNYINTTTL DQANFPPYGQ TFFGLPTGRF SDGRLISDFI AEYANLPLIP PFLEPGNSQK
KLYGVNFASA GAGALVETFQ GSVINLRTQL DHYKKVERLW RTNFGKEESK KRISRAVYLI
SIGSNDYSSI FLTNQSLPIS MSQHVDIVIG NLTTFIHEIY KIGGRKFGFL NVPDLGCFPA
LRILQPKNDD SCLRDASRLA SMHNRALTNL LFQMQRQVKG FKFSLFDMNK SLRLRMQHPS
KFGFKEGEEA CCGTGKWRGV FSCGGKRIVK EYQLCENPKD YIFWDSLHLT QNTYNQFANL
IWNGGHMSDS LVVGPYNINN LFQIP
