GIL1_ARATH
ID GIL1_ARATH Reviewed; 559 AA.
AC F4KGE8; Q8GWZ0; Q9FIL5;
DT 05-JUL-2017, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Protein GRAVITROPIC IN THE LIGHT 1 {ECO:0000303|PubMed:16640600};
GN Name=GIL1 {ECO:0000303|PubMed:16640600};
GN OrderedLocusNames=At5g58960 {ECO:0000312|Araport:AT5G58960};
GN ORFNames=K19M22.15 {ECO:0000312|EMBL:BAB09639.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=cv. Columbia, and cv. Wassilewskija;
RX PubMed=16640600; DOI=10.1111/j.1365-313x.2006.02727.x;
RA Allen T., Ingles P.J., Praekelt U., Smith H., Whitelam G.C.;
RT "Phytochrome-mediated agravitropism in Arabidopsis hypocotyls requires GIL1
RT and confers a fitness advantage.";
RL Plant J. 46:641-648(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [7]
RP GENE FAMILY.
RX PubMed=15618632; DOI=10.1271/bbb.68.2598;
RA Hattan J., Kanamoto H., Takemura M., Yokota A., Kohchi T.;
RT "Molecular characterization of the cytoplasmic interacting protein of the
RT receptor kinase IRK expressed in the inflorescence and root apices of
RT Arabidopsis.";
RL Biosci. Biotechnol. Biochem. 68:2598-2606(2004).
CC -!- FUNCTION: Required for red (R) and far red (FR) light-induced and
CC phytochrome-mediated deregulation of negative gravitropism leading to
CC randomization of hypocotyl growth orientation.
CC {ECO:0000269|PubMed:16640600}.
CC -!- INTERACTION:
CC F4KGE8; Q17TI5: BRX; NbExp=3; IntAct=EBI-25519238, EBI-4426649;
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=F4KGE8-1; Sequence=Displayed;
CC Name=2;
CC IsoId=F4KGE8-2; Sequence=VSP_059012;
CC -!- DISRUPTION PHENOTYPE: Maintenance of negative gravitropic hypocotyls
CC grow after exposure of seedlings to red (R) or far red (FR) light.
CC Reduced seedlings viability. {ECO:0000269|PubMed:16640600}.
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DR EMBL; DQ395085; ABD59217.1; -; Genomic_DNA.
DR EMBL; AB016885; BAB09639.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97121.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97122.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97123.1; -; Genomic_DNA.
DR EMBL; AK118548; BAC43150.1; -; mRNA.
DR EMBL; AY075634; AAL91642.1; -; mRNA.
DR EMBL; BT002623; AAO11539.1; -; mRNA.
DR EMBL; AK317383; BAH20054.1; -; mRNA.
DR RefSeq; NP_001032100.1; NM_001037023.1. [F4KGE8-2]
DR RefSeq; NP_200704.2; NM_125286.6. [F4KGE8-2]
DR RefSeq; NP_851217.1; NM_180886.2. [F4KGE8-1]
DR AlphaFoldDB; F4KGE8; -.
DR SMR; F4KGE8; -.
DR IntAct; F4KGE8; 1.
DR STRING; 3702.AT5G58960.1; -.
DR iPTMnet; F4KGE8; -.
DR PaxDb; F4KGE8; -.
DR PRIDE; F4KGE8; -.
DR ProteomicsDB; 220763; -. [F4KGE8-1]
DR EnsemblPlants; AT5G58960.1; AT5G58960.1; AT5G58960. [F4KGE8-1]
DR EnsemblPlants; AT5G58960.2; AT5G58960.2; AT5G58960. [F4KGE8-2]
DR EnsemblPlants; AT5G58960.3; AT5G58960.3; AT5G58960. [F4KGE8-2]
DR GeneID; 836013; -.
DR Gramene; AT5G58960.1; AT5G58960.1; AT5G58960. [F4KGE8-1]
DR Gramene; AT5G58960.2; AT5G58960.2; AT5G58960. [F4KGE8-2]
DR Gramene; AT5G58960.3; AT5G58960.3; AT5G58960. [F4KGE8-2]
DR KEGG; ath:AT5G58960; -.
DR Araport; AT5G58960; -.
DR TAIR; locus:2154583; AT5G58960.
DR eggNOG; ENOG502QUFA; Eukaryota.
DR InParanoid; F4KGE8; -.
DR OMA; GHIPGPI; -.
DR OrthoDB; 573246at2759; -.
DR PRO; PR:F4KGE8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4KGE8; baseline and differential.
DR GO; GO:0009959; P:negative gravitropism; IMP:TAIR.
DR GO; GO:0009639; P:response to red or far red light; IMP:TAIR.
DR InterPro; IPR006943; DUF641_pln.
DR InterPro; IPR040225; GIL1-like.
DR PANTHER; PTHR31161; PTHR31161; 1.
DR Pfam; PF04859; DUF641; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..559
FT /note="Protein GRAVITROPIC IN THE LIGHT 1"
FT /id="PRO_0000440950"
FT REGION 107..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..75
FT /note="Missing (in isoform 2)"
FT /id="VSP_059012"
FT CONFLICT 229
FT /note="D -> G (in Ref. 4; BAC43150)"
FT /evidence="ECO:0000305"
FT CONFLICT 297
FT /note="V -> A (in Ref. 4; BAC43150)"
FT /evidence="ECO:0000305"
FT CONFLICT 348
FT /note="D -> G (in Ref. 4; BAC43150)"
FT /evidence="ECO:0000305"
FT CONFLICT 394
FT /note="S -> G (in Ref. 4; BAC43150)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 559 AA; 62843 MW; B80478FD7D6587C3 CRC64;
MLPGILLCSL NPRNHSKKKK SERESLETEP KDIDYWYSVQ FNRDPPRFAL KSENNNHHSR
SKSGGDFCKK KKRGEMANKV SNFSDLIQRV TASCLLHPLS AGRQDLAVNR REEYDTEEEE
NEEEGEIQYE DALEKENGKD ETIRAKNGRN GVSVETVQEM EMVMDEVFTA AAAMKRAYVA
LQEAHSPWDP EKMHDADMAM VAELRRIGSL RERFRRMRGT GSGGRRKNDA GRGMLREAVA
PYEAVVKELK KEVKVKDTEI ENLKEKVKVA SMANGNGGKK HRLLSSRKVN CTTQIAVSPV
PELFEMTMIQ VKEASKSFTG ILLSLMRAAH WDIAAAVRSI EAASASSDGM SASSFASSVQ
SSVPNQHAKF ALESYICRKI FQGFDHETFY MDGSLSSLIN PDQYRRDCFA QFKDMKAMDP
MELLGILPTC HFGKFCSKKY LSIIHQKMEE SLFGDSEQRE LVVAGNHPRS QFYGEFLGLA
KAVWLLHLLA FSLDPSPSHF EANRGAEFHS QYMESVVRFS DGRVPAGQVV GFPVCPGFKL
SHQGKGSIIK SRVYLVPRA
