ID   GEP7_YEAS8              Reviewed;         287 AA.
AC   C8Z8J0;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Genetic interactor of prohibitin 7, mitochondrial;
DE   Flags: Precursor;
GN   Name=GEP7; ORFNames=EC1118_1G1_2366g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: Involved in respiratory growth and required for cell survival
CC       in the absence of prohibitins or GEM1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GEP7 family. {ECO:0000305}.
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DR   EMBL; FN393070; CAY79706.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8Z8J0; -.
DR   EnsemblFungi; CAY79706; CAY79706; EC1118_1G1_2366g.
DR   HOGENOM; CLU_064141_0_0_1; -.
DR   Proteomes; UP000000286; Chromosome VII, Scaffold EC1118_1G1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Transit peptide; Transmembrane;
KW   Transmembrane helix.
FT   TRANSIT         1..24
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..287
FT                   /note="Genetic interactor of prohibitin 7, mitochondrial"
FT                   /id="PRO_0000399744"
FT   TRANSMEM        250..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   287 AA;  32959 MW;  18DF55D2B5CF1FA5 CRC64;
     MVLSNVKIFR LKSHRAFRIG PMIKAVAGNL LVKRFYQPKL ERIPPASLLL KQKIRLAQNG
     STTSTENPIS FSQTMSEIFS VLQPSAPDLD EDETSGLKRD HLLTERLNNG ELGVIMNKFF
     NPSSTHNNQL IDTNILLQNF PKLSGNDLDL LDFAINEKMR GNWNDLKQDF IQLWYYKSFG
     FLGPRTQFVL TNSSPSLRSQ FLKLPFIEYN WFLLQNNKNA NILPADVQNV VKVFHLDDKR
     FSWKSIDPFS KAIISFVVFV SIYVWLDESA KQKTKELPAQ KSTVISE