ID   GEP7_ASHGO              Reviewed;         234 AA.
AC   Q75EB9;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Genetic interactor of prohibitin 7, mitochondrial;
DE   Flags: Precursor;
GN   Name=GEP7; OrderedLocusNames=AAR155W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in respiratory growth and required for cell survival
CC       in the absence of prohibitins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GEP7 family. {ECO:0000305}.
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DR   EMBL; AE016814; AAS50522.1; -; Genomic_DNA.
DR   RefSeq; NP_982698.1; NM_208051.1.
DR   AlphaFoldDB; Q75EB9; -.
DR   EnsemblFungi; AAS50522; AAS50522; AGOS_AAR155W.
DR   GeneID; 4618489; -.
DR   KEGG; ago:AGOS_AAR155W; -.
DR   eggNOG; ENOG502S4Y0; Eukaryota.
DR   HOGENOM; CLU_094335_0_0_1; -.
DR   InParanoid; Q75EB9; -.
DR   OMA; ERLTNIN; -.
DR   Proteomes; UP000000591; Chromosome I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Reference proteome; Transit peptide;
KW   Transmembrane; Transmembrane helix.
FT   TRANSIT         1..66
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           67..234
FT                   /note="Genetic interactor of prohibitin 7, mitochondrial"
FT                   /id="PRO_0000399737"
FT   TRANSMEM        192..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   234 AA;  26074 MW;  39D0BD78D5A3190F CRC64;
     MKRTCALASR AVPKSLLERQ ARRTGSKVGA SQEASKFVVA SLRDIGSLFS GSSSGDDEEQ
     EALRLHSDTV SKLNSGELTE VVRQRYCVDN KDRCETRMLL TKYPGPARER EMLQVATAEL
     SARDWRKMPR VWQQVSYYHA FGSWGPRTGL SFVGRRPEDF FVTDQKGLWT CSAPRRAEYE
     RSSRALDPAS RAVLYAAALV AAVAALGDLW RRQDADRQVT VAELDLAEPT SSPT