GEP5_YEAS2
ID GEP5_YEAS2 Reviewed; 293 AA.
AC C7GQR4;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 13-OCT-2009, sequence version 1.
DT 25-MAY-2022, entry version 24.
DE RecName: Full=Genetic interactor of prohibitin 5, mitochondrial;
DE AltName: Full=Required for respiratory growth protein 5;
GN Name=GEP5; Synonyms=RRG5; ORFNames=C1Q_02691;
OS Saccharomyces cerevisiae (strain JAY291) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=574961;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAY291;
RX PubMed=19812109; DOI=10.1101/gr.091777.109;
RA Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., Netto O.V.C.,
RA Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., Noronha M.F.,
RA Dominska M., Andrietta M.G.S., Andrietta S.R., Cunha A.F., Gomes L.H.,
RA Tavares F.C.A., Alcarde A.R., Dietrich F.S., McCusker J.H., Petes T.D.,
RA Pereira G.A.G.;
RT "Genome structure of a Saccharomyces cerevisiae strain widely used in
RT bioethanol production.";
RL Genome Res. 19:2258-2270(2009).
CC -!- FUNCTION: Essential for respiratory growth and required for maintenance
CC of mtDNA. Required for cell survival in the absence of prohibitins (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GEP5 family. {ECO:0000305}.
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DR EMBL; ACFL01000129; EEU06890.1; -; Genomic_DNA.
DR AlphaFoldDB; C7GQR4; -.
DR Proteomes; UP000008073; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0000002; P:mitochondrial genome maintenance; IEA:InterPro.
DR InterPro; IPR031455; Gep5.
DR Pfam; PF17053; GEP5; 1.
PE 3: Inferred from homology;
KW Mitochondrion.
FT CHAIN 1..293
FT /note="Genetic interactor of prohibitin 5, mitochondrial"
FT /id="PRO_0000399689"
SQ SEQUENCE 293 AA; 33882 MW; 6BF3784A4FDF2672 CRC64;
MASQVNALLL PVIESTPLHQ ITKVALTTTL TSKQSDYKFK EIAVPLTKSL QLYEKAQRRQ
DLRASLKALE SIIYQTHFQW NNPLPRHAHL FQKHYHFLLT HWPFENHRDL VDSIAVNNGK
LNSTSSRSVW LKADWITLFN VKNPWVQTPP SLMRLSGTDL DTFTPERIFL INSLGNHYKF
LIANSHLSYN HKKYPSPGVQ IPIRNALGEV SPAKQIAQLF ARQLSHIYKS LFIENPPLSP
ENELALTAVF YDETVERRLR RLYMRACARA YTTTNADSTT EPLMFHCTRW EVD