ID   GEP3_PICGU              Reviewed;         599 AA.
AC   A5DDR3;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Genetic interactor of prohibitins 3, mitochondrial;
DE   AltName: Full=Found in mitochondrial proteome protein 38;
DE   Flags: Precursor;
GN   Name=GEP3; Synonyms=FMP48; ORFNames=PGUG_01414;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: May be involved in the mitochondrial lipid metabolism.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH408156; EDK37316.2; -; Genomic_DNA.
DR   RefSeq; XP_001485743.1; XM_001485693.1.
DR   AlphaFoldDB; A5DDR3; -.
DR   SMR; A5DDR3; -.
DR   STRING; 4929.XP_001485743.1; -.
DR   EnsemblFungi; EDK37316; EDK37316; PGUG_01414.
DR   GeneID; 5128328; -.
DR   KEGG; pgu:PGUG_01414; -.
DR   eggNOG; ENOG502S0UP; Eukaryota.
DR   HOGENOM; CLU_025792_0_0_1; -.
DR   InParanoid; A5DDR3; -.
DR   OMA; QIVKYIP; -.
DR   OrthoDB; 612803at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..46
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           47..599
FT                   /note="Genetic interactor of prohibitins 3, mitochondrial"
FT                   /id="PRO_0000409638"
FT   DOMAIN          158..368
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   REGION          312..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   599 AA;  67005 MW;  BCCAD79CD1367087 CRC64;
     MLSLRRSIWI AACKRVSSFR TTIPIKSLHT NSQPVLSLRN VKFRPYSTIP LLQSLVPTCN
     SCGITLQKTD PDRPGFYREP GTGQKLVRKE NLVASNAYNG LDDDDLKLLL NSSGEEKDIS
     LFKQRNEPSP KVAPQSIQCI RCREAQFRSE YSQDEFPIES LDAIMTSLPP DAKLVYVISA
     ADFPMSLDSR VFSYRSALEI LFVITKCDLL FPTLNLANKY GLPFFQDYFY RKHGVSGENV
     VLTSGKIDWN IPTLLKNGKI RDNSYLIGSV NSGKSTLLKS MLSVSNKLAA KKQHLSSRER
     VKLEKEQDRL INSGASTPSD IRALRRKNEQ EKNRTGPGAS YMPGYTRGTI PYDVDGITMH
     DVPGFGENVD SNEFASLFSY LQPSQMKQLS KGVPIHKYGT YKSPFETIKG GQCYTVGGIF
     YMVPPPGTMV QARNCINHKA HIFSNVDKAK ASLEAVANED ENGAHAGLRN VFIMPGSALK
     KLVPRYIPAF YGAIDLVVAG AGHVNLTPTG APTPTDEPWI VWVPQGVRIW VRQPITRYIT
     RTLAGRDAKG NPLRKELWKQ KSVTHVERYT GKTPFYTRLS ANPDNTMATK DNRYPAWYE