ID   GEP3_KLULA              Reviewed;         550 AA.
AC   Q6CLQ8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 2.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Genetic interactor of prohibitins 3, mitochondrial;
DE   AltName: Full=Found in mitochondrial proteome protein 38;
DE   Flags: Precursor;
GN   Name=GEP3; Synonyms=FMP48; OrderedLocusNames=KLLA0F01144g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in the mitochondrial lipid metabolism.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAG97838.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; CR382126; CAG97838.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; XP_455131.1; XM_455131.1.
DR   AlphaFoldDB; Q6CLQ8; -.
DR   SMR; Q6CLQ8; -.
DR   STRING; 28985.XP_455131.1; -.
DR   EnsemblFungi; CAG97838; CAG97838; KLLA0_F01144g.
DR   GeneID; 2895862; -.
DR   KEGG; kla:KLLA0_F01144g; -.
DR   eggNOG; ENOG502S0UP; Eukaryota.
DR   HOGENOM; CLU_025792_1_0_1; -.
DR   InParanoid; Q6CLQ8; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:EnsemblFungi.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..43
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           44..550
FT                   /note="Genetic interactor of prohibitins 3, mitochondrial"
FT                   /id="PRO_0000409635"
FT   DOMAIN          107..298
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
SQ   SEQUENCE   550 AA;  62898 MW;  D14FBFF3ED438B39 CRC64;
     MKSRLQAFKQ FTRFVSCKSC GVELQSKNPS VTGYYKPPRA VRKDAGTIED LKYLMFTQEL
     QLKKHEIGLL DPDTDPDYKE PIPKRLVCKR CVDAISHNRY NSSDFPIHSF NDIKGALPHA
     ANVYHVVSLS DFPLSLDKTI LAEKNNRNYL LLSKADQITY KSSMLPHKGS AFFAEFCRRH
     IGVHVKKVVL FSNPRNWNIP SVINALAKRC YLLGNPNVGK TSLINSLLHE KSTSFQAQLD
     KRGNVIGPPK GHEQIQSTRR RAIFNEGGVS HIPNFTRTMQ TYLIEDKVVN DLPGYTMDPT
     KVSDLANYIE KETLDNIRKT SKFKIDKLIK QNYTSLTGSK TGKCLSFGGI FHLVPPNSTI
     NQVVNYIPLP EHEFSNVEKA VSLSLEVLQS ENHSLRQFFA LKKPFTDIKM FDRHVIPPFN
     GAIEIVLKDI GYFQVKPTGK YGFNGLYELW VPKGIRVCIR EPLSKLISKS YEKYIESGDI
     ADVCPTDRPL ISDTYIMNHT EEDTFARMRE MYINRTSKDI LSRRLLQKDP NDIVGTLQSP
     PSNLYWYYKW