ALMTE_ARATH
ID ALMTE_ARATH Reviewed; 543 AA.
AC Q9LS22; B3H4Y1; Q5XV16; Q5XV17;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Aluminum-activated malate transporter 14;
DE Short=AtALMT14;
GN Name=ALMT14; OrderedLocusNames=At5g46610; ORFNames=F10E10.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16740662; DOI=10.1073/pnas.0602868103;
RA Hoekenga O.A., Maron L.G., Pineros M.A., Cancado G.M., Shaff J.,
RA Kobayashi Y., Ryan P.R., Dong B., Delhaize E., Sasaki T., Matsumoto H.,
RA Yamamoto Y., Koyama H., Kochian L.V.;
RT "AtALMT1, which encodes a malate transporter, is identified as one of
RT several genes critical for aluminum tolerance in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:9738-9743(2006).
CC -!- FUNCTION: Malate transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=Q9LS22-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9LS22-2; Sequence=VSP_040189;
CC Name=3;
CC IsoId=Q9LS22-3; Sequence=VSP_040190;
CC -!- SIMILARITY: Belongs to the aromatic acid exporter (TC 2.A.85) family.
CC {ECO:0000305}.
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DR EMBL; AB028605; BAA97532.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95403.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95404.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95405.1; -; Genomic_DNA.
DR EMBL; AY735705; AAU44575.1; -; mRNA.
DR EMBL; AY735706; AAU44576.1; -; mRNA.
DR EMBL; DQ056708; AAY78854.1; -; mRNA.
DR RefSeq; NP_001032019.1; NM_001036942.1. [Q9LS22-2]
DR RefSeq; NP_001119385.1; NM_001125913.1. [Q9LS22-3]
DR RefSeq; NP_199473.1; NM_124031.2. [Q9LS22-1]
DR AlphaFoldDB; Q9LS22; -.
DR SMR; Q9LS22; -.
DR STRING; 3702.AT5G46610.1; -.
DR PaxDb; Q9LS22; -.
DR PRIDE; Q9LS22; -.
DR EnsemblPlants; AT5G46610.1; AT5G46610.1; AT5G46610. [Q9LS22-1]
DR EnsemblPlants; AT5G46610.2; AT5G46610.2; AT5G46610. [Q9LS22-2]
DR EnsemblPlants; AT5G46610.3; AT5G46610.3; AT5G46610. [Q9LS22-3]
DR GeneID; 834704; -.
DR Gramene; AT5G46610.1; AT5G46610.1; AT5G46610. [Q9LS22-1]
DR Gramene; AT5G46610.2; AT5G46610.2; AT5G46610. [Q9LS22-2]
DR Gramene; AT5G46610.3; AT5G46610.3; AT5G46610. [Q9LS22-3]
DR KEGG; ath:AT5G46610; -.
DR Araport; AT5G46610; -.
DR TAIR; locus:2142295; AT5G46610.
DR eggNOG; KOG4711; Eukaryota.
DR HOGENOM; CLU_020841_1_2_1; -.
DR InParanoid; Q9LS22; -.
DR OMA; SHQNETG; -.
DR OrthoDB; 516124at2759; -.
DR PhylomeDB; Q9LS22; -.
DR PRO; PR:Q9LS22; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LS22; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009705; C:plant-type vacuole membrane; IBA:GO_Central.
DR GO; GO:0034220; P:ion transmembrane transport; IEA:UniProt.
DR GO; GO:0015743; P:malate transport; IEA:InterPro.
DR InterPro; IPR020966; ALMT.
DR Pfam; PF11744; ALMT; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Ion channel; Ion transport; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..543
FT /note="Aluminum-activated malate transporter 14"
FT /id="PRO_0000401473"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..126
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 416..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 445..472
FT /evidence="ECO:0000255"
FT COMPBIAS 416..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 96..119
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3"
FT /id="VSP_040189"
FT VAR_SEQ 97..143
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000305"
FT /id="VSP_040190"
SQ SEQUENCE 543 AA; 60675 MW; 44C31A5AA8CE7A9E CRC64;
MSDRVHERSM GMEEEGSTKN MKTKVLELPT KIKKILKNIW KVGKDDPRRV KHALKVGVSL
TLVSLLYLME PLFKGIGNSA IWAVMTVVVV LEFSAGATLC KGLNRGLGTL IAGSLAFFIE
FVANDSGKIF RAIFIGAAVF IIGALITYLR FIPYIKKNYD YGMLIFLLTF NLITVSSYRV
DTVIKIAHER FYTIAMGVGI CLLMSLLVFP IWSGEDLHKS TVAKLQGLSY SIEACVNEYF
EEEEKDEETS DLSEDTIYNG YKTVLDSKSA DEALAMYASW EPRHTRHCHR FPWKHYVKVG
SVLRQFGYTV VALHGCLKTE IQTPRPLRGL FKDPCVRLAG EICKVLSELA ASIRNRRHCS
PEILSDSLQV ALQDLNTAIK SQPKLFLGSS QNGNVSQGNS GRHNPNVAVS QHINKDTNEA
ASYQNTGTPR GERMSRFGPN VSFSRLRADT LERRSAAATN ERKILRQQLS RIVVLTSLEF
SEALPFAAFA SLLVEMVARL DNVIEEVEEL GTIACFKDYD NNVDQKDVEV RVEKPADLVV
GVE
